Literature DB >> 29431424

Gadolinium-Free Contrast Agents for Magnetic Resonance Imaging of the Central Nervous System.

Eric M Gale1, Peter Caravan1.   

Abstract

We discuss how the recent revelation that gadolinium (Gd) from commercially available MRI contrast agents is irreversibly and cumulatively deposited in the central nervous system is driving innovation toward Gd-free contrast agents for neuroradiology.

Entities:  

Keywords:  GBCA; Gadolinium; central nervous system; magnetic resonance imaging

Mesh：

Substances：

Year:  2018        PMID： 29431424      PMCID： PMC5994911          DOI： 10.1021/acschemneuro.8b00044

Source DB:  PubMed          Journal:  ACS Chem Neurosci        ISSN： 1948-7193            Impact factor:   4.418


  5 in total

1.  Residual or retained gadolinium: practical implications for radiologists and our patients.

Authors:  Emanuel Kanal; Michael F Tweedle
Journal:  Radiology       Date:  2015-05-05       Impact factor: 11.105

Review 2.  Use of contrast media in neuroimaging.

Authors:  Marco Essig; Julien Dinkel; Juan E Gutierrez
Journal:  Magn Reson Imaging Clin N Am       Date:  2012-09-26       Impact factor: 2.266

Review 3.  Current and potential imaging applications of ferumoxytol for magnetic resonance imaging.

Authors:  Gerda B Toth; Csanad G Varallyay; Andrea Horvath; Mustafa R Bashir; Peter L Choyke; Heike E Daldrup-Link; Edit Dosa; John Paul Finn; Seymur Gahramanov; Mukesh Harisinghani; Iain Macdougall; Alexander Neuwelt; Shreyas S Vasanawala; Prakash Ambady; Ramon Barajas; Justin S Cetas; Jeremy Ciporen; Thomas J DeLoughery; Nancy D Doolittle; Rongwei Fu; John Grinstead; Alexander R Guimaraes; Bronwyn E Hamilton; Xin Li; Heather L McConnell; Leslie L Muldoon; Gary Nesbit; Joao P Netto; David Petterson; William D Rooney; Daniel Schwartz; Laszlo Szidonya; Edward A Neuwelt
Journal:  Kidney Int       Date:  2017-04-20       Impact factor: 10.612

4.  A Manganese-based Alternative to Gadolinium: Contrast-enhanced MR Angiography, Excretion, Pharmacokinetics, and Metabolism.

Authors:  Eric M Gale; Hsiao-Ying Wey; Ian Ramsay; Yi-Fen Yen; David E Sosnovik; Peter Caravan
Journal:  Radiology       Date:  2017-11-08       Impact factor: 11.105

5.  A Manganese Alternative to Gadolinium for MRI Contrast.

Authors:  Eric M Gale; Iliyana P Atanasova; Francesco Blasi; Ilknur Ay; Peter Caravan
Journal:  J Am Chem Soc       Date:  2015-12-04       Impact factor: 15.419
  5 in total
  6 in total

Review 1.  Current Strategies to Enhance Delivery of Drugs across the Blood-Brain Barrier.

Authors:  Raluca Ioana Teleanu; Manuela Daniela Preda; Adelina-Gabriela Niculescu; Oana Vladâcenco; Crina Ioana Radu; Alexandru Mihai Grumezescu; Daniel Mihai Teleanu
Journal:  Pharmaceutics       Date:  2022-05-04       Impact factor: 6.525

2.  Summary of Imaging in 2020: Visualizing the Future of Healthcare with MR Imaging.

Authors:  Brooke A Corbin; Alyssa C Pollard; Matthew J Allen; Mark D Pagel
Journal:  Mol Imaging Biol       Date:  2019-04       Impact factor: 3.488

3.  Manganese-Based Contrast Agents for Magnetic Resonance Imaging of Liver Tumors: Structure-Activity Relationships and Lead Candidate Evaluation.

Authors:  Junfeng Wang; Huan Wang; Ian A Ramsay; Derek J Erstad; Bryan C Fuchs; Kenneth K Tanabe; Peter Caravan; Eric M Gale
Journal:  J Med Chem       Date:  2018-09-25       Impact factor: 7.446

4.  Contrast-Free Detection of Focused Ultrasound-Induced Blood-Brain Barrier Opening Using Diffusion Tensor Imaging.

Authors:  Maria Eleni Karakatsani; Antonios N Pouliopoulos; Michael Liu; Sachin R Jambawalikar; Elisa E Konofagou
Journal:  IEEE Trans Biomed Eng       Date:  2021-07-16       Impact factor: 4.756

5.  Effective MR Molecular Imaging of Triple Negative Breast Cancer With an EDB-Fibronectin-Specific Contrast Agent at Reduced Doses.

Authors:  Nadia R Ayat; Amita Vaidya; Grace A Yeung; Megan N Buford; Ryan C Hall; Peter L Qiao; Xin Yu; Zheng-Rong Lu
Journal:  Front Oncol       Date:  2019-12-03       Impact factor: 6.244

6.  Thermodynamic Stability of Mn(II) Complexes with Aminocarboxylate Ligands Analyzed Using Structural Descriptors.

Authors:  Rocío Uzal-Varela; Francisco Pérez-Fernández; Laura Valencia; Aurora Rodríguez-Rodríguez; Carlos Platas-Iglesias; Peter Caravan; David Esteban-Gómez
Journal:  Inorg Chem       Date:  2022-08-22       Impact factor: 5.436
  6 in total

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