A Hendriks1, B Wijnen1, R van Engelen1, R Conde2,3, S M Evers1, J Gonzalez3, M Govers1, A Mühlbacher4, M Hiligsmann1. 1. a Department of Health Services Research , CAPHRI Care and Public Research Institute, Maastricht University , Maastricht , The Netherlands. 2. b Asistencia Cientifica de Alta Complejidad , Bogotá , Colombia. 3. c Universidad del Rosario , Bogotá , Colombia. 4. d Hochschule Neubrandenburg , Neubrandenburg , Germany.
Abstract
AIM: To elicit patients' preferences for HIV/AIDS treatment characteristics in Colombia. MATERIALS AND METHODS: A best-worst scaling case was used to provide a ranking of 26 HIV/AIDS treatment characteristics that were similar to a previous study conducted in Germany. In each choice task, participants were asked to choose the most important and the least important treatment characteristics from a set of five from the master list. Using the Hierarchical Bayes method, relative importance scores were calculated. Sub-group analyses were conducted according to sex, education, source of infection, symptoms, and age. RESULTS: A total of 195 patients fully completed the questionnaire. The three most important characteristics were "drug has very high efficacy" (relative importance score [RIS] = 10.1), "maximum prolongation of life expectancy" (RIS = 9.7), and "long duration of efficacy" (RIS = 7.4). Sub-group analysis showed only three significant (but minor) differences between older and younger people. CONCLUSION: This study suggests that treatment characteristics regarding efficacy and prolongation of life are particularly important for patients in Colombia. Further investigation on how patients make trade-offs between these important characteristics and incorporating this information in clinical and policy decision-making would be needed to improve adherence with HIV/AIDS medication.
AIM: To elicit patients' preferences for HIV/AIDS treatment characteristics in Colombia. MATERIALS AND METHODS: A best-worst scaling case was used to provide a ranking of 26 HIV/AIDS treatment characteristics that were similar to a previous study conducted in Germany. In each choice task, participants were asked to choose the most important and the least important treatment characteristics from a set of five from the master list. Using the Hierarchical Bayes method, relative importance scores were calculated. Sub-group analyses were conducted according to sex, education, source of infection, symptoms, and age. RESULTS: A total of 195 patients fully completed the questionnaire. The three most important characteristics were "drug has very high efficacy" (relative importance score [RIS] = 10.1), "maximum prolongation of life expectancy" (RIS = 9.7), and "long duration of efficacy" (RIS = 7.4). Sub-group analysis showed only three significant (but minor) differences between older and younger people. CONCLUSION: This study suggests that treatment characteristics regarding efficacy and prolongation of life are particularly important for patients in Colombia. Further investigation on how patients make trade-offs between these important characteristics and incorporating this information in clinical and policy decision-making would be needed to improve adherence with HIV/AIDS medication.
Authors: Hiba El Masri; Treasure M McGuire; Mieke L van Driel; Helen Benham; Samantha A Hollingworth Journal: Patient Prefer Adherence Date: 2022-09-20 Impact factor: 2.314
Authors: John M Humphrey; Violet Naanyu; Katherine R MacDonald; Kara Wools-Kaloustian; Gregory D Zimet Journal: PLoS One Date: 2019-10-30 Impact factor: 3.752