Mullai Baalaaji1, Muralidharan Jayashree2, Karthi Nallasamy1, Sunit Singhi1, Arun Bansal1. 1. Pediatric Emergency and Intensive Care Units, Department of Pediatrics, Post Graduate Institute of Medical Education and Research, Chandigarh, India. 2. Pediatric Emergency and Intensive Care Units, Department of Pediatrics, Post Graduate Institute of Medical Education and Research, Chandigarh, India. Correspondence to: Dr Jayashree Muralidharan, Professor and Chief, Pediatric Emergency and Intensive Care Units, Department of Pediatrics, Post Graduate Institute of Medical Education and Research, Chandigarh, India. mjshree@hotmail.com.
Abstract
OBJECTIVE: To identify predictors and outcome of acute kidney injury (AKI) in children with diabetic ketoacidosis (DKA) admitted to a Pediatric Intensive Care Unit (PICU). METHODS: Retrospective case review of 79 children with DKA admitted between 2011-2014. RESULTS: Twenty eight children developed AKI during the hospital stay; 20 (71.4%) recovered with hydration alone. Serum chloride at 24 hours was independently associated with AKI. Children with AKI had prolonged acidosis and PICU stay and higher mortality. CONCLUSION: Majority of children with AKI and DKA, recover with hydration. Hyperchloremia at 24 hours had independent association with AKI, although cause-effect relation could not be ascertained.
OBJECTIVE: To identify predictors and outcome of acute kidney injury (AKI) in children with diabetic ketoacidosis (DKA) admitted to a Pediatric Intensive Care Unit (PICU). METHODS: Retrospective case review of 79 children with DKA admitted between 2011-2014. RESULTS: Twenty eight children developed AKI during the hospital stay; 20 (71.4%) recovered with hydration alone. Serum chloride at 24 hours was independently associated with AKI. Children with AKI had prolonged acidosis and PICU stay and higher mortality. CONCLUSION: Majority of children with AKI and DKA, recover with hydration. Hyperchloremia at 24 hours had independent association with AKI, although cause-effect relation could not be ascertained.
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