Pavle Z Mašković1, Vesna Veličković2, Saša Đurović3, Zoran Zeković4, Marija Radojković4, Aleksandra Cvetanović4, Jaroslava Švarc-Gajić4, Milan Mitić5, Jelena Vujić6. 1. University of Kragujevac, Faculty of Agronomy, Department of Food Technology, Cara Dušana 34, 32000 Čačak, Serbia. Electronic address: pavlem@kg.ac.rs. 2. University of Kragujevac, Faculty of Science, Department of Chemistry, Radoja Domanovića 12, 34000 Kragujevac, Serbia. 3. University of Novi Sad, Faculty of Technology, Bulevar Cara Lazara 1, 21000 Novi Sad, Serbia; Institute of General and Phaysical Chemistry, Studentski trg 12/V, 11158 Serbia. Electronic address: sasatfns@uns.ac.rs. 4. University of Novi Sad, Faculty of Technology, Bulevar Cara Lazara 1, 21000 Novi Sad, Serbia. 5. University of Niš, Faculty of Science and Mathematics, Višegradska 33, 18000 Niš, Serbia. 6. University of Kragujevac, Faculty of Agronomy, Department of Chemistry and Chemical Engineering, Cara Dušana 34, 32000 Čačak, Serbia.
Abstract
BACKGROUND: Lavatera thuringiaca L. is herbaceous perennial plant from Malvaceae family, which is known for its biological activity and richness in polyphenolic compounds. Despite this, the information regarding the biological activity and chemical profile is still insufficient. PURPOSE: Aim of this study was to investigate biological potential and chemical profile of Lavatera thuringiaca L., as well as influence of applied extraction technique on them. STUDY DESIGN AND METHODS: Two conventional and four non-conventional extraction techniques were applied in order to obtain extracts rich in bioactive compound. Extracts were further tested for total phenolics, flavonoids, condensed tannins, gallotannins and anthocyanins contents using spectrophotometric assays. Polyphenolic profile was established using HPLC-DAD analysis. Biological activity was investigated regarding antioxidant, cytotoxic and antibacterial activities. Four antioxidant assays were applied as well as three different cell lines for cytotoxic and fifteen bacterial strain for antibacterial activity. RESULTS AND CONCLUSION: Results showed that subcritical water extraction (SCW) dominated over the other extraction techniques, where SCW extract exhibited the highest biological activity. Study indicates that plant Lavatera thuringiaca L. may be used as a potential source of biologically compounds.
BACKGROUND:Lavatera thuringiaca L. is herbaceous perennial plant from Malvaceae family, which is known for its biological activity and richness in polyphenolic compounds. Despite this, the information regarding the biological activity and chemical profile is still insufficient. PURPOSE: Aim of this study was to investigate biological potential and chemical profile of Lavatera thuringiaca L., as well as influence of applied extraction technique on them. STUDY DESIGN AND METHODS: Two conventional and four non-conventional extraction techniques were applied in order to obtain extracts rich in bioactive compound. Extracts were further tested for total phenolics, flavonoids, condensed tannins, gallotannins and anthocyanins contents using spectrophotometric assays. Polyphenolic profile was established using HPLC-DAD analysis. Biological activity was investigated regarding antioxidant, cytotoxic and antibacterial activities. Four antioxidant assays were applied as well as three different cell lines for cytotoxic and fifteen bacterial strain for antibacterial activity. RESULTS AND CONCLUSION: Results showed that subcritical water extraction (SCW) dominated over the other extraction techniques, where SCW extract exhibited the highest biological activity. Study indicates that plant Lavatera thuringiaca L. may be used as a potential source of biologically compounds.
Authors: Maria Fraga-Corral; Paula García-Oliveira; Antia G Pereira; Catarina Lourenço-Lopes; Cecilia Jimenez-Lopez; Miguel Angel Prieto; Jesus Simal-Gandara Journal: Molecules Date: 2020-01-30 Impact factor: 4.411
Authors: Norelhouda Abderrezag; Jose David Sánchez-Martínez; Ouahida Louaer; Abdeslam-Hassen Meniai; Jose A Mendiola Journal: Molecules Date: 2021-11-17 Impact factor: 4.411
Authors: Moldir A Zhandabayeva; Kaldanay K Kozhanova; Assyl K Boshkayeva; Valeriy A Kataev; Gulbaram O Ustenova; Nadezhda G Gemejiyeva; Zhanar A Iskakbayeva Journal: Int J Biomater Date: 2021-07-21