Sandra H van Oostrom1, Astrid C J Nooyens2, Martin P J van Boxtel3, W M Monique Verschuren4. 1. Center for Nutrition, Prevention and Health Services, National Institute for Public Health and the Environment, Bilthoven, The Netherlands. Electronic address: sandra.van.oostrom@rivm.nl. 2. Center for Nutrition, Prevention and Health Services, National Institute for Public Health and the Environment, Bilthoven, The Netherlands. 3. Department of Psychiatry and Neuropsychology, Maastricht University, Maastricht, The Netherlands. 4. Center for Nutrition, Prevention and Health Services, National Institute for Public Health and the Environment, Bilthoven, The Netherlands; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
Abstract
OBJECTIVES: In older adults, both short and long sleep duration are associated with lower cognitive function, suggesting an inverted U-shaped association between sleep duration and cognitive outcomes. This study examined whether sleep duration is associated with (changes in) cognitive function in a middle-aged population. METHODS: In the Doetinchem Cohort Study, the cognitive function of 2970 men and women aged 41-75 years at baseline (1995-2007) was examined 2-3 times, with 5-year time intervals. Global cognitive function and the domains memory, information processing speed, and cognitive flexibility were assessed. In multivariable linear regression models, (change in) self-reported sleep duration was studied in association with the level and change in cognitive function. In a subsample of the population (n = 2587), the association of sleep duration and feeling rested with cognitive function was studied. RESULTS: Sleep duration of 9 h and more was statistically significantly associated with lower global cognitive function (p < 0.01), memory (p = 0.02), and flexibility (p = 0.03), compared to a sleep duration of 7 or 8 h. Among adults feeling frequently not well rested, both short and long sleep duration were associated with a lower speed of cognitive function. An inverted U-shaped association between sleep duration and cognitive function was observed for speed, flexibility, and global cognitive function. Sleep duration was not associated with change in cognitive function. CONCLUSIONS: Middle-age adults with long sleep duration had a lower cognitive function.
OBJECTIVES: In older adults, both short and long sleep duration are associated with lower cognitive function, suggesting an inverted U-shaped association between sleep duration and cognitive outcomes. This study examined whether sleep duration is associated with (changes in) cognitive function in a middle-aged population. METHODS: In the Doetinchem Cohort Study, the cognitive function of 2970 men and women aged 41-75 years at baseline (1995-2007) was examined 2-3 times, with 5-year time intervals. Global cognitive function and the domains memory, information processing speed, and cognitive flexibility were assessed. In multivariable linear regression models, (change in) self-reported sleep duration was studied in association with the level and change in cognitive function. In a subsample of the population (n = 2587), the association of sleep duration and feeling rested with cognitive function was studied. RESULTS: Sleep duration of 9 h and more was statistically significantly associated with lower global cognitive function (p < 0.01), memory (p = 0.02), and flexibility (p = 0.03), compared to a sleep duration of 7 or 8 h. Among adults feeling frequently not well rested, both short and long sleep duration were associated with a lower speed of cognitive function. An inverted U-shaped association between sleep duration and cognitive function was observed for speed, flexibility, and global cognitive function. Sleep duration was not associated with change in cognitive function. CONCLUSIONS: Middle-age adults with long sleep duration had a lower cognitive function.
Authors: Alberto R Ramos; Wassim Tarraf; Benson Wu; Susan Redline; Jianwen Cai; Martha L Daviglus; Linda Gallo; Yasmin Mossavar-Rahmani; Krista M Perreira; Phyllis Zee; Donglin Zeng; Hector M Gonzalez Journal: Alzheimers Dement Date: 2020-01-06 Impact factor: 21.566
Authors: Tina T Vo; Shandell Pahlen; William S Kremen; Matt McGue; Anna Dahl Aslan; Marianne Nygaard; Kaare Christensen; Chandra A Reynolds Journal: Sleep Date: 2022-10-10 Impact factor: 6.313
Authors: Tianyue Guan; Chao Zhang; Xuanmin Zou; Chen Chen; Li Zhou; Xiaochang Wu; Jiahu Hao Journal: Int J Environ Res Public Health Date: 2022-10-01 Impact factor: 4.614
Authors: Bernhard Grässler; Milos Dordevic; Fabian Herold; Sabine Darius; Corinna Langhans; Nicole Halfpaap; Berit K Labott; Patrick Müller; Achraf Ammar; Beatrice Thielmann; Irina Böckelmann; Notger G Müller; Anita Hökelmann Journal: Int J Environ Res Public Health Date: 2021-12-17 Impact factor: 3.390