Literature DB >> 2942467

Detection of brain autoantibodies in the serum of patients with Alzheimer's disease but not Down's syndrome.

V K Singh, H H Fudenberg.   

Abstract

The immunofluorescent staining of antibodies specifically binding to rat brain tissue sections was investigated in 95 human sera including 30 cases of Alzheimer's disease. A high incidence of specific antibrain antibody was found among Alzheimer's patients (57% positive) compared to other neurological disease controls (only 8% positive) or normal young and aged healthy controls (none positive).

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Year:  1986        PMID： 2942467     DOI： 10.1016/0165-2478(86)90030-1

Source DB:  PubMed          Journal:  Immunol Lett        ISSN： 0165-2478            Impact factor:   3.685


  4 in total

1.  Immunocytochemical detection of anti-hippocampal antibodies in Alzheimer's disease and normal cerebrospinal fluid.

Authors:  D A Loeffler; P L Juneau; H U Nguyen; D Najman; N Pomara; P A LeWitt
Journal:  Neurochem Res       Date:  1997-02       Impact factor: 3.996

2.  Antibodies in cerebrospinal fluid of some Alzheimer disease patients recognize cholinergic neurons in the rat central nervous system.

Authors:  A McRae-Degueurce; S Booj; K Haglid; L Rosengren; J E Karlsson; I Karlsson; A Wallin; L Svennerholm; C G Gottfries; A Dahlstrom
Journal:  Proc Natl Acad Sci U S A       Date:  1987-12       Impact factor: 11.205

3.  Studies of neuroimmune markers in Alzheimer's disease.

Authors:  V K Singh
Journal:  Mol Neurobiol       Date:  1994 Aug-Dec       Impact factor: 5.590

4.  Autoantibodies to neurofibrillary tangles and brain tissue in Alzheimer's disease. Establishment of Epstein-Barr virus-transformed antibody-producing cell lines.

Authors:  F Gaskin; B S Kingsley; S M Fu
Journal:  J Exp Med       Date:  1987-01-01       Impact factor: 14.307
  4 in total

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