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Literature DB >> 2942462

Immune induction of Ia antigens in activated T cells and in kidney epithelial cells in mice.

Abstract

A rat monoclonal antibody against mouse Ia antigens was used to investigate the induction of Ia expression by activated T cells and renal epithelial cells during immune responses. The induction of low levels of surface Ia on activated helper and cytotoxic/suppressor T-cell phenotypes was directly demonstrated by differential fluorescence staining. Renal epithelial cells were observed to become strongly Ia-positive after primary immunization with alum-precipitated protein antigen, or after secondary challenge with the soluble antigen used for priming.

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Year: 1986 PMID： 2942462 PMCID： PMC1453098

Source DB: PubMed Journal: Immunology ISSN： 0019-2805 Impact factor: 7.397

25 in total

1. Occurrence of Ia antigens on tissues on non-lymphoid origin.

Authors: K Wiman; B Curman; U Forsum; L Klareskog; U Malmnäs-Tjernlund; L Rask; L Trägårdh; P A Peterson
Journal: Nature Date: 1978-12-14 Impact factor: 49.962

2. Peroxidase labelled antibody and Fab conjugates with enhanced intracellular penetration.

Authors: S Avrameas; T Ternynck
Journal: Immunochemistry Date: 1971-12

3. Functional differences associated with quantitative distribution of Ia antigens on mouse B cells.

Authors: E M Andrew; N M Mackenzie; R M Parkhouse
Journal: Adv Exp Med Biol Date: 1985 Impact factor: 2.622

4. Differential effects of interferon on the expression of H-2K, H-2D, and Ia antigens on mouse lymphocytes.

Authors: F Vignaux; I Gresser
Journal: J Immunol Date: 1977-02 Impact factor: 5.422

5. Ia determinants on human T-cell subsets defined by monoclonal antibody. Activation stimuli required for expression.

Authors: E L Reinherz; P C Kung; J M Pesando; J Ritz; G Goldstein; S F Schlossman
Journal: J Exp Med Date: 1979-12-01 Impact factor: 14.307

6. "Ia-like" antigens on human T cells.

Authors: M F Greaves; W Verbi; H Festenstein; C Papasteriadis; D Jaraquemada; A Hayward
Journal: Eur J Immunol Date: 1979-05 Impact factor: 5.532

7. Detection of HLA-DRw (Ia-like) antigens on human T lymphocytes grown in tissue culture.

Authors: R S Metzgar; J Bertoglio; J K Anderson; G D Bonnard; F W Ruscetti
Journal: J Immunol Date: 1979-03 Impact factor: 5.422

8. Murine plasma cells secreting more than one class of immunoglobulin heavy chain. II. SAMM 368--a plasmacytoma secreting IgG2b-kappa and IgA-kappa immunoglobulins which do not share idiotypic determinants.

Authors: H C Morse; M E Neiders; R Lieberman; A R Lawton; R Asofsky
Journal: J Immunol Date: 1977-05 Impact factor: 5.422

9. Biotinylinsulins as potential tools for receptor studies.

Authors: K Hofmann; F M Finn; H J Friesen; C Diaconescu; H Zahn
Journal: Proc Natl Acad Sci U S A Date: 1977-07 Impact factor: 11.205

10. Identification of a novel cell type in peripheral lymphoid organs of mice. V. Purification of spleen dendritic cells, new surface markers, and maintenance in vitro.

Authors: R M Steinman; G Kaplan; M D Witmer; Z A Cohn
Journal: J Exp Med Date: 1979-01-01 Impact factor: 14.307

3 in total