| Literature DB >> 2942414 |
T Yamada, K Nakao, N Morii, H Itoh, S Shiono, M Sakamoto, A Sugawara, Y Saito, H Ohno, A Kanai.
Abstract
The effect of intracerebroventricular (i.c.v.) treatment of alpha-human atrial natriuretic polypeptide on the vasopressin secretion induced by i.c.v. injection of angiotensin II was studied in conscious, unrestrained rats. Pretreatment of alpha-human atrial natriuretic polypeptide (5 micrograms) significantly inhibited the angiotensin II (100 ng)-stimulated vasopressin secretion. This result suggests that atrial natriuretic polypeptide plays regulatory roles in vasopressin secretion in the central nervous system.Entities:
Mesh:
Substances:
Year: 1986 PMID: 2942414 DOI: 10.1016/0014-2999(86)90802-2
Source DB: PubMed Journal: Eur J Pharmacol ISSN: 0014-2999 Impact factor: 4.432