Literature DB >> 2942412

Suppression of lordosis behavior by the putative 5-HT receptor agonist 8-OH-DPAT in the rat.

S Ahlenius, A Fernandez-Guasti, S Hjorth, K Larsson.   

Abstract

The administration of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT), inhibited the lordosis induced by estradiol benzoate or estradiol benzoate plus progesterone in ovariectomized rats. There was no facilitation of lordosis by 8-OH-DPAT in animals pretreated with a threshold dose of estradiol benzoate. The results are consistent with the view that 8-OH-DPAT is an agonist at 5-HT receptors and provide further support for an inhibition role of central 5-HT in the mediation of lordosis behavior.

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Year:  1986        PMID： 2942412     DOI： 10.1016/0014-2999(86)90241-4

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  7 in total

1.  Flibanserin and 8-OH-DPAT implicate serotonin in association between female marmoset monkey sexual behavior and changes in pair-bond quality.

Authors:  Yves Aubert; Morgan L Gustison; Lindsey A Gardner; Michael A Bohl; Jason R Lange; Kelly A Allers; Bernd Sommer; Nicole A Datson; David H Abbott
Journal:  J Sex Med       Date:  2012-02-03       Impact factor: 3.802

2.  Positron emission tomography assessment of 8-OH-DPAT-mediated changes in an index of cerebral glucose metabolism in female marmosets.

Authors:  Alexander K Converse; Yves Aubert; Mohammed Farhoud; Jamey P Weichert; Ian J Rowland; Nicole M Ingrisano; Kelly A Allers; Bernd Sommer; David H Abbott
Journal:  Neuroimage       Date:  2012-01-02       Impact factor: 6.556

Review 3.  Pharmacology of serotonin and female sexual behavior.

Authors:  Lynda Uphouse
Journal:  Pharmacol Biochem Behav       Date:  2013-11-15       Impact factor: 3.533

4.  Differential effects of the serotonin1A agonist, 8-OH-DPAT, on masculine and feminine sexual behavior of the ferret.

Authors:  R G Paredes; E Kica; M J Baum
Journal:  Psychopharmacology (Berl)       Date:  1994-05       Impact factor: 4.530

5.  Evidence for the involvement of central 5-HT1A receptors in the mediation of lordosis behavior in the female rat.

Authors:  S Ahlenius; K Larsson; A Fernandez-Guasti
Journal:  Psychopharmacology (Berl)       Date:  1989       Impact factor: 4.530

6.  Modulation of sexual behaviour in the rat by a potent and selective alpha 2-adrenoceptor antagonist, delequamine (RS-15385-197).

Authors:  D Tallentire; G McRae; M Spedding; R Clark; B Vickery
Journal:  Br J Pharmacol       Date:  1996-05       Impact factor: 8.739

7.  Sex differences in the reversal of fluoxetine-induced anorexia following raphe injections of 8-OH-DPAT.

Authors:  Paul J Currie; Melissa Braver; Aaisha Mirza; Krisna Sricharoon
Journal:  Psychopharmacology (Berl)       Date:  2003-11-28       Impact factor: 4.530
  7 in total

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