Literature DB >> 29423615

Defining spasticity: a new approach considering current movement disorders terminology and botulinum toxin therapy.

Dirk Dressler1, Roongroj Bhidayasiri2, Saeed Bohlega3, Pedro Chana4, Hsin Fen Chien5, Tae Mo Chung6, Carlo Colosimo7, Markus Ebke8, Klemens Fedoroff9, Bernd Frank10, Ryuji Kaji11, Petr Kanovsky12, Serdar Koçer13, Federico Micheli14, Olga Orlova15, Sebastian Paus16, Zvezdan Pirtosek17, Maja Relja18, Raymond L Rosales19, José Alberto Sagástegui-Rodríguez20, Paul W Schoenle21, Gholam Ali Shahidi22, Sofia Timerbaeva23, Uwe Walter24, Fereshte Adib Saberi25.   

Abstract

Spasticity is a symptom occurring in many neurological conditions including stroke, multiple sclerosis, hypoxic brain damage, traumatic brain injury, tumours and heredodegenerative diseases. It affects large numbers of patients and may cause major disability. So far, spasticity has merely been described as part of the upper motor neurone syndrome or defined in a narrowed neurophysiological sense. This consensus organised by IAB-Interdisciplinary Working Group Movement Disorders wants to provide a brief and practical new definition of spasticity-for the first time-based on its various forms of muscle hyperactivity as described in the current movement disorders terminology. We propose the following new definition system: Spasticity describes involuntary muscle hyperactivity in the presence of central paresis. The involuntary muscle hyperactivity can consist of various forms of muscle hyperactivity: spasticity sensu strictu describes involuntary muscle hyperactivity triggered by rapid passive joint movements, rigidity involuntary muscle hyperactivity triggered by slow passive joint movements, dystonia spontaneous involuntary muscle hyperactivity and spasms complex involuntary movements usually triggered by sensory or acoustic stimuli. Spasticity can be described by a documentation system grouped along clinical picture (axis 1), aetiology (axis 2), localisation (axis 3) and additional central nervous system deficits (axis 4). Our new definition allows distinction of spasticity components accessible to BT therapy and those inaccessible. The documentation sheet presented provides essential information for planning of BT therapy.

Entities:  

Keywords:  Botulinum toxin therapy; Contractures; Dystonia; Rigidity; Spasms; Spasticity; Treatment

Mesh:

Substances:

Year:  2018        PMID: 29423615     DOI: 10.1007/s00415-018-8759-1

Source DB:  PubMed          Journal:  J Neurol        ISSN: 0340-5354            Impact factor:   4.849


  14 in total

1.  Hyper-reflexia without spasticity after unilateral infarct of the medullary pyramid.

Authors:  S J Sherman; G F Koshland; J F Laguna
Journal:  J Neurol Sci       Date:  2000-04-15       Impact factor: 3.181

Review 2.  Clinical applications of botulinum toxin.

Authors:  Dirk Dressler
Journal:  Curr Opin Microbiol       Date:  2012-07-05       Impact factor: 7.934

3.  Effects of phenol solutions on the nerve roots of the cat: an electrophysiological and histological study.

Authors:  P W Nathan; T A Sears; M C Smith
Journal:  J Neurol Sci       Date:  1965 Jan-Feb       Impact factor: 3.181

Review 4.  Delta-9-Tetrahydrocannabinol/Cannabidiol Oromucosal Spray (Sativex®): A Review in Multiple Sclerosis-Related Spasticity.

Authors:  Gillian M Keating
Journal:  Drugs       Date:  2017-04       Impact factor: 9.546

5.  Outcome of selective motor fasciculotomy in the treatment of upper limb spasticity.

Authors:  Aneel Kumar Puligopu; Anirudh Kumar Purohit
Journal:  J Pediatr Neurosci       Date:  2011-10

Review 6.  OnabotulinumtoxinA muscle injection patterns in adult spasticity: a systematic literature review.

Authors:  Luba Nalysnyk; Spyridon Papapetropoulos; Philip Rotella; Jason C Simeone; Katharine E Alter; Alberto Esquenazi
Journal:  BMC Neurol       Date:  2013-09-08       Impact factor: 2.474

Review 7.  Safety and efficacy of incobotulinumtoxinA as a potential treatment for poststroke spasticity.

Authors:  Andrea Santamato
Journal:  Neuropsychiatr Dis Treat       Date:  2016-01-27       Impact factor: 2.570

8.  Safety and efficacy of incobotulinumtoxinA doses up to 800 U in limb spasticity: The TOWER study.

Authors:  Jörg Wissel; Djamel Bensmail; Joaquim J Ferreira; Franco Molteni; Lalith Satkunam; Susana Moraleda; Tiina Rekand; John McGuire; Astrid Scheschonka; Birgit Flatau-Baqué; Olivier Simon; Edward T J Rochford; Dirk Dressler; David M Simpson
Journal:  Neurology       Date:  2017-03-10       Impact factor: 9.910

9.  Effects of repeated abobotulinumtoxinA injections in upper limb spasticity.

Authors:  Jean-Michel Gracies; Michael O'Dell; Michele Vecchio; Peter Hedera; Serdar Kocer; Monika Rudzinska-Bar; Bruce Rubin; Sofiya L Timerbaeva; Anna Lusakowska; François Constant Boyer; Anne-Sophie Grandoulier; Claire Vilain; Philippe Picaut
Journal:  Muscle Nerve       Date:  2017-08-13       Impact factor: 3.217

10.  Incidence estimate and guideline-oriented treatment for post-stroke spasticity: an analysis based on German statutory health insurance data.

Authors:  Veronika Egen-Lappe; Ingrid Köster; Ingrid Schubert
Journal:  Int J Gen Med       Date:  2013-03-13
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  13 in total

1.  Comparative functional analysis of mice after local injection with botulinum neurotoxin A1, A2, A6, and B1 by catwalk analysis.

Authors:  Molly S Moritz; William H Tepp; Heather N'te Inzalaco; Eric A Johnson; Sabine Pellett
Journal:  Toxicon       Date:  2019-06-07       Impact factor: 3.033

2.  Nociplastic Pain in Multiple Sclerosis Spasticity: Dermatomal Evaluation, Treatment with Intradermal Saline Injection and Outcomes Assessed by 3D Gait Analysis: Review and a Case Report.

Authors:  Paolo De Blasiis; Giampaolo de Sena; Elisabetta Signoriello; Felice Sirico; Marta Imamura; Giacomo Lus
Journal:  Int J Environ Res Public Health       Date:  2022-06-27       Impact factor: 4.614

3.  Nabiximols and botulinum toxin injections for patients with multiple sclerosis: efficacy on spasticity and spasms in a single-centre experience.

Authors:  Arianna Sartori; Alessandro Dinoto; Lara Stragapede; Giulia Mazzon; Maria Elisa Morelli; Fulvio Pasquin; Alessio Bratina; Antonio Bosco; Paolo Manganotti
Journal:  Neurol Sci       Date:  2021-03-19       Impact factor: 3.307

Review 4.  Critical Analysis of Neuronal Cell and the Mouse Bioassay for Detection of Botulinum Neurotoxins.

Authors:  Sabine Pellett; William H Tepp; Eric A Johnson
Journal:  Toxins (Basel)       Date:  2019-12-07       Impact factor: 4.546

5.  Reliability and Validity of the Modified Heckmatt Scale in Evaluating Muscle Changes With Ultrasound in Spasticity.

Authors:  Marisa C Moreta; Alana Fleet; Rajiv Reebye; Gina McKernan; Michael Berger; Jordan Farag; Michael C Munin
Journal:  Arch Rehabil Res Clin Transl       Date:  2020-07-01

6.  Prevalence and Risk Factors for Spasticity After Stroke: A Systematic Review and Meta-Analysis.

Authors:  Huangling Zeng; Jian Chen; Yang Guo; Sheng Tan
Journal:  Front Neurol       Date:  2021-01-20       Impact factor: 4.003

Review 7.  Muscle Tone Physiology and Abnormalities.

Authors:  Jacky Ganguly; Dinkar Kulshreshtha; Mohammed Almotiri; Mandar Jog
Journal:  Toxins (Basel)       Date:  2021-04-16       Impact factor: 4.546

8.  Synergic use of botulinum toxin injection and radial extracorporeal shockwave therapy in Multiple Sclerosis spasticity.

Authors:  Cinzia Marinaro; Cosimo Costantino; Oriana D'Esposito; Marianna Barletta; Angelo Indino; Gerardo De Scorpio; Antonio Ammendolia
Journal:  Acta Biomed       Date:  2021-01-28

9.  Isolation and Characterization of the Novel Botulinum Neurotoxin A Subtype 6.

Authors:  Molly S Moritz; William H Tepp; Marite Bradshaw; Eric A Johnson; Sabine Pellett
Journal:  mSphere       Date:  2018-10-24       Impact factor: 4.389

10.  Individualized OnabotulinumtoxinA Treatment for Upper Limb Spasticity Resulted in High Clinician- and Patient-Reported Satisfaction: Long-Term Observational Results from the ASPIRE Study.

Authors:  Gerard E Francisco; Wolfgang H Jost; Ganesh Bavikatte; Daniel S Bandari; Simon F T Tang; Michael C Munin; Joan Largent; Aubrey M Adams; Aleksej Zuzek; Alberto Esquenazi
Journal:  PM R       Date:  2020-02-27       Impact factor: 2.298

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