| Literature DB >> 2942334 |
D F Liew, C S Ng, S H Heng, S S Ratnam.
Abstract
The metabolic effects of an injectable contraceptive, Depo-provera (medroxyprogesterone acetate), an oral contraceptive pill containing 50 micrograms ethinyl estradiol and 500 micrograms norgestrel and a control group (not on contraceptives) were compared in 3 groups, each comprising 32 women. The subjects were matched for race, age and parity. Mean duration of treatment was 41.7 +/- 18.3 months for Depo-provera and 59.6 +/- 29.0 months for the pill group. Glucose tolerance was impaired in both treatment groups. The combination pill showed more changes in both glucose tolerance and insulin response. Lipid levels remained unchanged in both treatment groups.Entities:
Keywords: Age Factors; Anthropometry; Asia; Biology; Body Weight; Carbohydrate Metabolic Effects; Comparative Studies; Contraception; Contraceptive Agents; Contraceptive Agents, Estrogen--administraction and dosage; Contraceptive Agents, Female; Contraceptive Agents, Progestin--administraction and dosage; Contraceptive Agents--administraction and dosage; Contraceptive Methods--side effects; Depo-provera--administraction and dosage; Developing Countries; Diseases; Endocrine System; Ethinyl Estradiol--administraction and dosage; Evaluation; Examinations And Diagnoses; Family Planning; Fertility Measurements; Glucose Tolerance Test--analysis; Hormones; Injectables--side effects; Laboratory Examinations And Diagnoses; Laboratory Procedures; Lipid Metabolic Effects; Lipids; Measurement; Medroxyprogesterone Acetate; Metabolic Effects; Norgestrel--administraction and dosage; Parity; Physiology; Population Characteristics; Reproductive Control Agents; Research Methodology; Singapore; Southeastern Asia; Studies
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Year: 1986 PMID： 2942334 DOI： 10.1016/0010-7824(86)90101-0
Source DB: PubMed Journal: Contraception ISSN： 0010-7824 Impact factor: 3.375