Literature DB >> 29423281

Occurrence of sudden paraplegia during follow-up period of thoracic vertebral compression fracture in a case with spinal epidural lipomatosis.

Sugita Shurei1, Kiyofumi Yamakawa1, Takahiro Hozumi1, Takahiro Goto1.   

Abstract

INTRODUCTION: Spinal epidural lipomatosis (SEL) involves hypertrophy of fat tissue in the extradural space, often associated with long-term corticosteroid therapy. Sometimes it causes severe spinal cord compression and the patient gradually becomes symptomatic. However, sudden onset of neurological deterioration is extremely rare. CASE
PRESENTATION: We herein present a case of sudden paraplegia in a patient with thoracic SEL at 2 months after thoracic vertebral fracture, whose symptoms were consistent with a lesion at the same level as the SEL. Computed tomography scan showed no remarkable change in the degree of vertebral fracture at the time of neurological deterioration. We performed immediate decompression surgery and found hemorrhage and granulation tissue at the level of the fracture and removed it with the epidural fat tissue. The hematoma and granulation tissue were thought to be the cause of the acute deterioration. The patient recovered gradually from the paraplegia. DISCUSSION: Sudden paraplegia with SEL at the time of vertebral fracture has previously been reported, but this is the first report of SEL with delayed onset of paraplegia after an initial diagnosis of coexisting vertebral fracture.

Entities:  

Year:  2017        PMID: 29423281      PMCID: PMC5798904          DOI: 10.1038/s41394-017-0001-3

Source DB:  PubMed          Journal:  Spinal Cord Ser Cases        ISSN: 2058-6124


  7 in total

1.  Acute spinal cord compression due to epidural lipomatosis complicated by an abscess: magnetic resonance and pathology findings.

Authors:  Giulio Zuccoli; Nicolò Pipitone; Nicola De Carli; Luigi Vecchia; Stefano C Bartoletti
Journal:  Eur Spine J       Date:  2010-04-06       Impact factor: 3.134

Review 2.  Bisphosphonates for steroid-induced osteoporosis.

Authors:  Claire S Allen; James Hs Yeung; Ben Vandermeer; Joanne Homik
Journal:  Cochrane Database Syst Rev       Date:  2016-10-05

3.  Acute paraplegia due to an extradural spinal lipoma: case report.

Authors:  Y V Meisheri; S Mehta; K Chattopadhyay
Journal:  Spinal Cord       Date:  1996-10       Impact factor: 2.772

4.  Idiopathic spinal epidural lipomatosis: urgent decompression in an atypical case.

Authors:  A López-González; M Resurrección Giner
Journal:  Eur Spine J       Date:  2007-09-18       Impact factor: 3.134

Review 5.  Spinal epidural lipomatosis--a brief review.

Authors:  Darweesh Al-Khawaja; Kevin Seex; Guy D Eslick
Journal:  J Clin Neurosci       Date:  2008-10-26       Impact factor: 1.961

6.  Sudden paraplegia following epidural lipomatosis and thoracal compression fracture after long-term steroid therapy: a case report.

Authors:  Suat Erol Celik; Sait B Erer; Ilker Güleç; Recai Gökcan; Sait Naderi
Journal:  Rheumatol Int       Date:  2009-12-12       Impact factor: 2.631

7.  Delayed neurological deficits induced by an epidural hematoma associated with a thoracic osteoporotic compression fracture.

Authors:  Min-Soo Kang; Yong-Hwan Shin; Choon-Dae Lee; Sang-Ho Lee
Journal:  Neurol Med Chir (Tokyo)       Date:  2012       Impact factor: 1.742

  7 in total

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