Naveed Kamal1, Neil Majmundar1, Nitesh Damadora1, Mohammad El-Ghanem1, Rolla Nuoman2, Irwin A Keller3, Steven Schonfeld3, Igor Rybinnik4, Gaurav Gupta5, Sudipta Roychowdry3, Fawaz Al-Mufti1,4. 1. a Department of Neurosurgery , Rutgers University, New Jersey Medical School , Newark , NJ , USA. 2. b Department of Neurology , Rutgers University, New Jersey Medical School , Newark , NJ , USA. 3. c Department of Radiology , Rutgers University, Robert Wood Johnson Medical School , New Brunswick , NJ , USA. 4. d Department of Neurology , Rutgers University, Robert Wood Johnson Medical School , New Brunswick , NJ , USA. 5. e Department of Neurosurgery , Rutgers University, Robert Wood Johnson Medical School , New Brunswick , NJ , USA.
Abstract
PURPOSE: The purpose of this study is to review the history of treatments for acute ischemic stroke, examine developments in endovascular therapy, and discuss the future of the management of acute ischemic stroke. METHODS: A selective review of recent clinical trials for the treatment of acute ischemic stroke was conducted. RESULTS: We reviewed completed trials of the management of acute ischemic stroke including intravenous thrombolytics, intraarterial thrombolytics, and thrombectomy. We also assessed the future direction of research by reviewing ongoing clinical trials. CONCLUSIONS: The advancement of endovascular treatment for stroke has led to improved morbidity and mortality for patients. Future challenges include delivering these treatments to stroke centers worldwide.
PURPOSE: The purpose of this study is to review the history of treatments for acute ischemic stroke, examine developments in endovascular therapy, and discuss the future of the management of acute ischemic stroke. METHODS: A selective review of recent clinical trials for the treatment of acute ischemic stroke was conducted. RESULTS: We reviewed completed trials of the management of acute ischemic stroke including intravenous thrombolytics, intraarterial thrombolytics, and thrombectomy. We also assessed the future direction of research by reviewing ongoing clinical trials. CONCLUSIONS: The advancement of endovascular treatment for stroke has led to improved morbidity and mortality for patients. Future challenges include delivering these treatments to stroke centers worldwide.
Entities:
Keywords:
Stroke; endovascular therapy; epidemiology; history
Authors: Mohammad El-Ghanem; Francisco E Gomez; Prateeka Koul; Rolla Nuoman; Justin G Santarelli; Krishna Amuluru; Chirag D Gandhi; Eric R Cohen; Philip Meyers; Fawaz Al-Mufti Journal: Interv Neurol Date: 2018-12-13