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Literature DB >> 2941689

Non-specific immunosuppression in experimental cryptococcosis in rats.

D T Masih, H R Rubinstein, C E Sotomayor, M E Ferro, C M Riera.

Abstract

The delayed type hypersensitivity response to human serum albumin (HSA) of rats infected intraperitoneally with 10(7) viable C. neoformans cells, and 7 days after, immunized with human serum albumin was significantly diminished (p less than 0.05) when compared with the response observed in rats immunized with human serum albumin and non infected. The spleen mononuclear cells from suppressed rats transferred to normal syngeneic recipients of the same sex suppress the afferent phase of the response (p less than 0.02) suggesting that cells present in the spleen might be one of the responsible mechanisms for the suppression to non-related antigens in infected animals.

Entities: Disease Gene Species

Mesh：

Substances：
Serum Albumin

Year: 1986 PMID： 2941689 DOI： 10.1007/bf00437371

Source DB: PubMed Journal: Mycopathologia ISSN： 0301-486X Impact factor: 2.574

22 in total

1. DETECTION OF CRYPTOCOCCUS NEOFORMANS ANTIGEN IN BODY FLUIDS BY LATEX PARTICLE AGGLUTINATION.

Authors: N BLOOMFIELD; M A GORDON; D F ELMENDORF
Journal: Proc Soc Exp Biol Med Date: 1963-10

2. Micromethods for the study of proteins and antibodies. I. Procedure and general applications of hemagglutination and hemagglutination-inhibition reactions with tannic acid and protein-treated red blood cells.

Authors: A B STAVITSKY
Journal: J Immunol Date: 1954-05 Impact factor: 5.422

3. Factors influencing killing of Cryptococcus neoformans by human leukocytes in vitro.

Authors: R D Diamond; R K Root; J E Bennett
Journal: J Infect Dis Date: 1972-04 Impact factor: 5.226

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Authors: J R Graybill; R H Alford
Journal: Cell Immunol Date: 1974-10 Impact factor: 4.868

5. Immunoregulation in disseminated histoplasmosis: characterization of splenic suppressor cell populations.

Authors: D A Nickerson; R A Havens; W E Bullock
Journal: Cell Immunol Date: 1981-05-15 Impact factor: 4.868

6. Response of congenitally athymic (nude) and phenotypically normal mice to Cryptococcus neoformans infection.

Authors: L K Cauley; J W Murphy
Journal: Infect Immun Date: 1979-03 Impact factor: 3.441

7. Transfer of immunity to cryptococcosis by T-enriched splenic lymphocytes from Cryptococcus neoformans-sensitized mice.

Authors: T S Lim; J W Murphy
Journal: Infect Immun Date: 1980-10 Impact factor: 3.441

8. Experimental cryptococcosis in guinea pigs.

Authors: C M Riera; D T Masih; R Nobile
Journal: Mycopathologia Date: 1983-06-20 Impact factor: 2.574

9. Immunization of mice by intracutaneous inoculation with viable virulent Cryptococcus neoformans: immunological and histopathological parameters.

Authors: S A Moser; F L Lyon; J E Domer; J E Williams
Journal: Infect Immun Date: 1982-02 Impact factor: 3.441

10. Immunosuppression by avirulent, pseudohyphal forms of Cryptococcus neoformans.

Authors: R Blackstock; N K Hall
Journal: Mycopathologia Date: 1982-11-19 Impact factor: 2.574

5 in total

1. Immunosuppression in experimental cryptococcosis in rats. Induction of thymic suppressor cells.

Authors: C E Sotomayor; H R Rubinstein; L Cervi; C M Riera; D T Masih
Journal: Mycopathologia Date: 1989-10 Impact factor: 2.574

2. Modulation of I-A and I-E expression in macrophages by T-suppressor cells induced in Cryptococcus neoformans infected rats.

Authors: H R Rubinstein; C E Sotomayor; L A Cervi; C M Riera; D T Masih
Journal: Mycopathologia Date: 1993-09 Impact factor: 2.574

3. Immunosuppression, interleukin-10 synthesis and apoptosis are induced in rats inoculated with Cryptococcus neoformans glucuronoxylomannan.

Authors: Laura S Chiapello; José L Baronetti; María P Aoki; Susana Gea; Héctor Rubinstein; Diana T Masih
Journal: Immunology Date: 2004-11 Impact factor: 7.397

4. Immunosuppression in experimental cryptococcosis in rats: modification of macrophage functions by T suppressor cells. Macrophages functions in cryptococcosis.

Authors: H R Rubinstein; C E Sotomayor; L A Cervi; C M Riera; D T Masih
Journal: Mycopathologia Date: 1989-10 Impact factor: 2.574

5. Immunosuppression in experimental cryptococcosis in rats. Induction of efferent T suppressor cells to a non-related antigen.

Authors: D T Masih; C E Sotomayor; H R Rubinstein; C M Riera
Journal: Mycopathologia Date: 1991-06 Impact factor: 2.574

5 in total