Literature DB >> 29416266

Aging and the Krüppel-like factors.

Paishiun N Hsieh1,2, David R Sweet1,2, Liyan Fan1,2, Mukesh K Jain1.   

Abstract

The mammalian Krüppel-like factors (KLFs) are a family of zinc-finger containing transcription factors with diverse patterns of expression and a wide array of cellular functions. While their roles in mammalian physiology are well known, there is a growing appreciation for their roles in modulating the fundamental progression of aging. Here we review the current knowledge of Krüppel-like factors with a focus on their roles in processes regulating aging and age-associated diseases.

Entities:  

Keywords:  KLF; Krüppel-like transcription factors; aging; aging-associated disease; chronic disease; healthspan; lifespan

Year:  2017        PMID： 29416266      PMCID： PMC5798252     

Source DB:  PubMed          Journal:  Trends Cell Mol Biol        ISSN： 0972-8449


  176 in total

1.  Aging: a theory based on free radical and radiation chemistry.

Authors:  D HARMAN
Journal:  J Gerontol       Date:  1956-07

2.  Comparative and meta-analytic insights into life extension via dietary restriction.

Authors:  Shinichi Nakagawa; Malgorzata Lagisz; Katie L Hector; Hamish G Spencer
Journal:  Aging Cell       Date:  2012-02-22       Impact factor: 9.304

3.  Kruppel-like factor 2 (KLF2) regulates monocyte differentiation and functions in mBSA and IL-1β-induced arthritis.

Authors:  M Das; J Lu; M Joseph; R Aggarwal; S Kanji; B K McMichael; B S Lee; S Agarwal; A Ray-Chaudhury; O H Iwenofu; P Kuppusamy; V J Pompili; M K Jain; H Das
Journal:  Curr Mol Med       Date:  2012-02       Impact factor: 2.222

Review 4.  Evolutionary medicine: from dwarf model systems to healthy centenarians?

Authors:  Valter D Longo; Caleb E Finch
Journal:  Science       Date:  2003-02-28       Impact factor: 47.728

Review 5.  The role of protein clearance mechanisms in organismal ageing and age-related diseases.

Authors:  David Vilchez; Isabel Saez; Andrew Dillin
Journal:  Nat Commun       Date:  2014-12-08       Impact factor: 14.919

Review 6.  The senescence-associated secretory phenotype: the dark side of tumor suppression.

Authors:  Jean-Philippe Coppé; Pierre-Yves Desprez; Ana Krtolica; Judith Campisi
Journal:  Annu Rev Pathol       Date:  2010       Impact factor: 23.472

7.  KLF4 modulates expression of IL-6 in dendritic cells via both promoter activation and epigenetic modification.

Authors:  Jason M Rosenzweig; Justin D Glenn; Peter A Calabresi; Katharine A Whartenby
Journal:  J Biol Chem       Date:  2013-07-11       Impact factor: 5.157

Review 8.  Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases.

Authors:  Claudio Franceschi; Judith Campisi
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2014-06       Impact factor: 6.053

9.  KLF4-SQSTM1/p62-associated prosurvival autophagy contributes to carfilzomib resistance in multiple myeloma models.

Authors:  Irene Riz; Teresa S Hawley; Robert G Hawley
Journal:  Oncotarget       Date:  2015-06-20

10.  Krüppel-like factor 6 is a transcriptional activator of autophagy in acute liver injury.

Authors:  Svenja Sydor; Paul Manka; Jan Best; Sami Jafoui; Jan-Peter Sowa; Miguel Eugenio Zoubek; Virginia Hernandez-Gea; Francisco Javier Cubero; Julia Kälsch; Diana Vetter; Maria Isabel Fiel; Yujin Hoshida; C Billie Bian; Leonard J Nelson; Han Moshage; Klaas Nico Faber; Andreas Paul; Hideo A Baba; Guido Gerken; Scott L Friedman; Ali Canbay; Lars P Bechmann
Journal:  Sci Rep       Date:  2017-08-14       Impact factor: 4.379
View more
  6 in total

Review 1.  The Krüppel-Like Factors and Control of Energy Homeostasis.

Authors:  Paishiun N Hsieh; Liyan Fan; David R Sweet; Mukesh K Jain
Journal:  Endocr Rev       Date:  2019-02-01       Impact factor: 19.871

Review 2.  Aberrant miRNAs Regulate the Biological Hallmarks of Glioblastoma.

Authors:  Wanli Yu; Sai Liang; Chunzhi Zhang
Journal:  Neuromolecular Med       Date:  2018-09-04       Impact factor: 3.843

Review 3.  Molecular link between circadian clocks and cardiac function: a network of core clock, slave clock, and effectors.

Authors:  Weiyi Xu; Mukesh K Jain; Lilei Zhang
Journal:  Curr Opin Pharmacol       Date:  2020-11-12       Impact factor: 5.547

4.  KLF-1 orchestrates a xenobiotic detoxification program essential for longevity of mitochondrial mutants.

Authors:  Marija Herholz; Estela Cepeda; Linda Baumann; Alexandra Kukat; Johannes Hermeling; Sarah Maciej; Karolina Szczepanowska; Victor Pavlenko; Peter Frommolt; Aleksandra Trifunovic
Journal:  Nat Commun       Date:  2019-07-25       Impact factor: 14.919

5.  KLF11 deficiency enhances chemokine generation and fibrosis in murine unilateral ureteral obstruction.

Authors:  Silvana B De Lorenzo; Alyssa M Vrieze; Ruth A Johnson; Karen R Lien; Karl A Nath; Vesna D Garovic; Khashayarsha Khazaie; Joseph P Grande
Journal:  PLoS One       Date:  2022-04-12       Impact factor: 3.240

6.  Aging and pathological aging signatures of the brain: through the focusing lens of SIRT6.

Authors:  Daniel Stein; Amir Mizrahi; Anastasia Golova; Adam Saretzky; Alfredo Garcia Venzor; Zeev Slobodnik; Shai Kaluski; Monica Einav; Ekaterina Khrameeva; Debra Toiber
Journal:  Aging (Albany NY)       Date:  2021-03-09       Impact factor: 5.682
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.