Literature DB >> 29415850

Patterns of co-occurring addictions, posttraumatic stress disorder, and major depressive disorder in detoxification treatment seekers: Implications for improving detoxification treatment outcomes.

RaeAnn E Anderson1, Bryce Hruska1, Alec P Boros2, Christopher J Richardson2, Douglas L Delahanty3.   

Abstract

BACKGROUND AND OBJECTIVES: Poly-substance use and psychiatric comorbidity are common among individuals receiving substance detoxification services. Posttraumatic stress disorder (PTSD) and major depressive disorder (MDD) are the most common co-occurring psychiatric disorders with substance use disorder (SUD). Current treatment favors a one-size-fits-all approach to treating addiction focusing on one substance or one comorbidity. Research examining patterns of substance use and comorbidities can inform efforts to effectively identify and differentially treat individuals with co-occurring conditions.
METHODS: Using latent class analysis, the current study identified four patterns of PTSD, MDD, and substance use among 375 addiction treatment seekers receiving medically supervised detoxification.
RESULTS: The four identified classes were: 1) a PTSD-MDD-Poly SUD class characterized by PTSD and MDD occurring in the context of opioid, cannabis, and tobacco use disorders; 2) an MDD-Poly SUD class characterized by MDD and alcohol, opioid, tobacco, and cannabis use disorders; 3) an alcohol-tobacco class characterized by alcohol and tobacco use disorders; and 4) an opioid-tobacco use disorder class characterized by opioid and tobacco use disorders. The observed classes differed on gender and clinical characteristics including addiction severity, trauma history, and PTSD/MDD symptom severity. DISCUSSION AND
CONCLUSIONS: The observed classes likely require differing treatment approaches. For example, people in the PTSD-MDD-Poly SUD class would likely benefit from treatment approaches targeting anxiety sensitivity and distress tolerance, while the opioid-tobacco class would benefit from treatments that incorporate motivational interviewing. Appropriate matching of treatment to class could optimize treatment outcomes for polysubstance and comorbid psychiatric treatment seekers. These findings also underscore the importance of well-developed referral networks to optimize outpatient psychotherapy for detoxification treatment-seekers to enhance long-term recovery, particularly those that include transdiagnostic treatment components.
Copyright © 2017. Published by Elsevier Inc.

Entities:  

Keywords:  Detoxification; Latent class analysis; PTSD; Polysubstance use; Treatment

Mesh:

Year:  2017        PMID: 29415850     DOI: 10.1016/j.jsat.2017.12.009

Source DB:  PubMed          Journal:  J Subst Abuse Treat        ISSN: 0740-5472


  8 in total

1.  Heterogeneity in the Co-occurrence of Substance Use and Posttraumatic Stress Disorder: A Latent Class Analysis Approach.

Authors:  Ateka A Contractor; Nicole H Weiss; Katherine L Dixon-Gordon; Heidemarie Blumenthal
Journal:  J Dual Diagn       Date:  2019-03-06

2.  The opioid and related drug epidemics in rural Appalachia: A systematic review of populations affected, risk factors, and infectious diseases.

Authors:  Christine A Schalkoff; Kathryn E Lancaster; Bradley N Gaynes; Vivian Wang; Brian W Pence; William C Miller; Vivian F Go
Journal:  Subst Abus       Date:  2019-08-12       Impact factor: 3.716

3.  Randomized controlled trial of enhanced telephone monitoring with detoxification patients: 3- and 6-month outcomes.

Authors:  Christine Timko; Maureen Below; Lisa Vittorio; Emmeline Taylor; Grace Chang; Steven Lash; Fe Erlita D Festin; Deborah Brief
Journal:  J Subst Abuse Treat       Date:  2019-01-04

4.  Mechanisms and Clinical Features of Co-occurring Opioid and Nicotine Use.

Authors:  Sarah D Lichenstein; Yasmin Zakiniaeiz; Sarah W Yip; Kathleen A Garrison
Journal:  Curr Addict Rep       Date:  2019-04-27

5.  Diagnostic and Predictive Neuroimaging Biomarkers for Posttraumatic Stress Disorder.

Authors:  Sigal Zilcha-Mano; Xi Zhu; Benjamin Suarez-Jimenez; Alison Pickover; Shachaf Tal; Sara Such; Caroline Marohasy; Marika Chrisanthopoulos; Chloe Salzman; Amit Lazarov; Yuval Neria; Bret R Rutherford
Journal:  Biol Psychiatry Cogn Neurosci Neuroimaging       Date:  2020-04-11

6.  Coping strategy utilization among posttraumatic stress disorder symptom severity and substance use co-occurrence typologies: A latent class analysis.

Authors:  Nathan T Kearns; Ateka A Contractor; Nicole H Weiss; Heidemarie Blumenthal
Journal:  Psychol Trauma       Date:  2020-09-07

7.  Evaluating the influences of major depression and posttraumatic stress disorder on trauma and alcohol cue reactivity.

Authors:  Hanaan Bing-Canar; Alexander Demos; Robin J Mermelstein; Erin C Berenz
Journal:  Addict Behav       Date:  2020-08-01       Impact factor: 3.913

Review 8.  Trauma-focused psychotherapies for post-traumatic stress disorder: A systematic review and network meta-analysis.

Authors:  Brooke Jericho; Aileen Luo; David Berle
Journal:  Acta Psychiatr Scand       Date:  2021-09-17       Impact factor: 7.734

  8 in total

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