Aditya Kurade1, Sara Dhanawade1, Sachin Shetti2. 1. Department of Pediatrics, Bharati Vidyapeeth Deemed University Medical College and Hospital, Sangli, Maharashtra 416416, India. 2. Department of Physiotherapy, Bharati Vidyapeeth Deemed University Medical College and Hospital, Sangli, Maharashtra 416416, India.
Abstract
OBJECTIVE: The objective of this articlewas to study the success, tolerability of sputum induction and the bacterial isolates of induced sputum in children aged <5 years. METHODS: The cross-sectional study included 120 hospitalized children aged 1-59 months meeting WHO criteria for pneumonia. Sputum induction was performed using hypertonic (3%) saline. RESULTS: Mean age of the subjects was 19.5 months (2-59 months). Overall success of sputum induction was 53.3% and highest (64.28%) in 37-59 months age group. Adverse events such as tachypnea, hypoxemia (SpO2 <90) and vomiting were observed in 41.6, 17.5 and 15.8%, respectively. A potential pathogen was isolated in 45 (70.3%) of 64 cases with good quality sputum. Klebsiella pneumoniae was the commonest (38.2%) followed by Streptococcus pneumoniae (14.8%) and others. CONCLUSION: Sputum induction in young children is safe and feasible in Indian settings. While the success was limited, bacterial yield was high.
OBJECTIVE: The objective of this articlewas to study the success, tolerability of sputum induction and the bacterial isolates of induced sputum in children aged <5 years. METHODS: The cross-sectional study included 120 hospitalized children aged 1-59 months meeting WHO criteria for pneumonia. Sputum induction was performed using hypertonic (3%) saline. RESULTS: Mean age of the subjects was 19.5 months (2-59 months). Overall success of sputum induction was 53.3% and highest (64.28%) in 37-59 months age group. Adverse events such as tachypnea, hypoxemia (SpO2 <90) and vomiting were observed in 41.6, 17.5 and 15.8%, respectively. A potential pathogen was isolated in 45 (70.3%) of 64 cases with good quality sputum. Klebsiella pneumoniae was the commonest (38.2%) followed by Streptococcus pneumoniae (14.8%) and others. CONCLUSION: Sputum induction in young children is safe and feasible in Indian settings. While the success was limited, bacterial yield was high.
Authors: Wongani Nyangulu; Herbert Thole; Angella Chikhoza; Mike Msakwiza; James Nyirenda; Mphatso Chisala; Pui-Ying Iroh Tam Journal: Trans R Soc Trop Med Hyg Date: 2021-11-01 Impact factor: 2.184