| Literature DB >> 2941463 |
T Q Nguyen, K E Greer, G B Fisher, P H Cooper.
Abstract
The Papillon-Lefèvre syndrome is an autosomal recessive disorder characterized by diffuse palmoplantar keratoderma and premature loss of both the deciduous and the permanent teeth. We report two female patients with Papillon-Lefèvre syndrome in whom treatment with oral isotretinoin produced remarkable improvement of the keratoderma within 2 weeks.Entities:
Mesh：
Substances：
Year: 1986 PMID： 2941463 DOI： 10.1016/s0190-9622(86)70140-0
Source DB: PubMed Journal: J Am Acad Dermatol ISSN： 0190-9622 Impact factor: 11.527