| Literature DB >> 29413009 |
Rishi D Naik1, Douglas L Seidner1, Dawn Wiese Adams2.
Abstract
Celiac disease is an autoimmune disorder due to the inflammatory response to gluten in genetically predisposed individuals. It causes an enteropathy associated with several nutritional complications. Strict compliance to a gluten-free diet (GFD) is the current primary therapy. Nonceliac gluten sensitivity (NCGS) is a condition in which gluten ingestion leads to systemic symptoms but is not associated with small bowel atrophy or abnormal celiac serologies. A GFD heals celiac disease enteropathy and improves symptoms in NCGS. However, a long-term GFD can be associated with nutritional deficiencies and requires monitoring and guidance.Entities:
Keywords: Celiac; Drug development; Gluten; Gluten-free diet; Nonceliac gluten sensitivity; Nutritional deficiencies
Mesh:
Substances:
Year: 2017 PMID: 29413009 DOI: 10.1016/j.gtc.2017.09.006
Source DB: PubMed Journal: Gastroenterol Clin North Am ISSN: 0889-8553 Impact factor: 3.806