Literature DB >> 29412886

Pathology-Based Research in Africa.

Maria P Lemos1, Terrie E Taylor2, Suzanne M McGoldrick3, Malcolm E Molyneux4, Manoj Menon5, Steve Kussick6, Nonhlanhla N Mkhize7, Neil A Martinson8, Andrea Stritmatter9, Julie Randolph-Habecker10.   

Abstract

The process of conducting pathology research in Africa can be challenging. But the rewards in terms of knowledge gained, quality of collaborations, and impact on communities affected by infectious disease and cancer are great. This report reviews 3 different research efforts: fatal malaria in Malawi, mucosal immunity to HIV in South Africa, and cancer research in Uganda. What unifies them is the use of pathology-based approaches to answer vital questions, such as physiology, pathogenesis, predictors of clinical course, and diagnostic testing schemes.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Burkitt lymphoma; Cancer; HIV/AIDS; Histopathology; Infectious disease; Malaria; Pathology

Mesh：

Year:  2018        PMID： 29412886      PMCID： PMC5894888          DOI： 10.1016/j.cll.2017.10.006

Source DB:  PubMed          Journal:  Clin Lab Med        ISSN： 0272-2712            Impact factor:   1.935


  60 in total

1.  Innate immune activation enhances hiv acquisition in women, diminishing the effectiveness of tenofovir microbicide gel.

Authors:  Vivek Naranbhai; Salim S Abdool Karim; Marcus Altfeld; Natasha Samsunder; Raveshni Durgiah; Sengeziwe Sibeko; Quarraisha Abdool Karim; William H Carr
Journal:  J Infect Dis       Date:  2012-07-24       Impact factor: 5.226

Review 2.  Role of pathology in improving health care in poor resource environments.

Authors:  Mandong Barnabas; Joseph A Ngbea; Emmanuel Innocent; Keziah N Malu
Journal:  Niger J Med       Date:  2014 Jul-Sep

3.  DNA/NYVAC vaccine regimen induces HIV-specific CD4 and CD8 T-cell responses in intestinal mucosa.

Authors:  Matthieu Perreau; Hugh C Welles; Alexandre Harari; Olivia Hall; Ricardo Martin; Michel Maillard; Gian Dorta; Pierre-Alexandre Bart; Eric J Kremer; Jim Tartaglia; Ralf Wagner; Mariano Esteban; Yves Levy; Giuseppe Pantaleo
Journal:  J Virol       Date:  2011-07-20       Impact factor: 5.103

4.  Cancer survival in Africa, Asia, and Central America: a population-based study.

Authors:  Rengaswamy Sankaranarayanan; Rajaraman Swaminathan; Hermann Brenner; Kexin Chen; Kee Seng Chia; Jian Guo Chen; Stephen C K Law; Yoon-Ok Ahn; Yong Bing Xiang; Balakrishna B Yeole; Hai Rim Shin; Viswanathan Shanta; Ze Hong Woo; Nimit Martin; Yupa Sumitsawan; Hutcha Sriplung; Adolfo Ortiz Barboza; Sultan Eser; Bhagwan M Nene; Krittika Suwanrungruang; Padmavathiamma Jayalekshmi; Rajesh Dikshit; Henry Wabinga; Divina B Esteban; Adriano Laudico; Yasmin Bhurgri; Ebrima Bah; Nasser Al-Hamdan
Journal:  Lancet Oncol       Date:  2009-12-10       Impact factor: 41.316

5.  Poor hormone receptor expression in East African breast cancer: evidence of a biologically different disease?

Authors:  P A Bird; A G Hill; N Houssami
Journal:  Ann Surg Oncol       Date:  2008-04-12       Impact factor: 5.344

6.  Clinical features and prognostic indicators in paediatric cerebral malaria: a study of 131 comatose Malawian children.

Authors:  M E Molyneux; T E Taylor; J J Wirima; A Borgstein
Journal:  Q J Med       Date:  1989-05

7.  Measuring mortality due to HIV-associated tuberculosis among adults in South Africa: Comparing verbal autopsy, minimally-invasive autopsy, and research data.

Authors:  Aaron S Karat; Mpho Tlali; Katherine L Fielding; Salome Charalambous; Violet N Chihota; Gavin J Churchyard; Yasmeen Hanifa; Suzanne Johnson; Kerrigan McCarthy; Neil A Martinson; Tanvier Omar; Kathleen Kahn; Daniel Chandramohan; Alison D Grant
Journal:  PLoS One       Date:  2017-03-23       Impact factor: 3.240

8.  Inflammatory genital infections mitigate a severe genetic bottleneck in heterosexual transmission of subtype A and C HIV-1.

Authors:  Richard E Haaland; Paulina A Hawkins; Jesus Salazar-Gonzalez; Amber Johnson; Amanda Tichacek; Etienne Karita; Olivier Manigart; Joseph Mulenga; Brandon F Keele; George M Shaw; Beatrice H Hahn; Susan A Allen; Cynthia A Derdeyn; Eric Hunter
Journal:  PLoS Pathog       Date:  2009-01-23       Impact factor: 6.823

9.  Differential blood and mucosal immune responses against an HIV-1 vaccine administered via inguinal or deltoid injection.

Authors:  Otto O Yang; F Javier Ibarrondo; Charles Price; Lance E Hultin; Julie Elliott; Patricia M Hultin; Roger Shih; Mary Ann Hausner; Hwee L Ng; Jennifer Hoffman; Beth D Jamieson; Peter A Anton
Journal:  PLoS One       Date:  2014-02-18       Impact factor: 3.240

10.  In men at risk of HIV infection, IgM, IgG1, IgG3, and IgA reach the human foreskin epidermis.

Authors:  M P Lemos; S T Karuna; G J Mize; Y Fong; S M Montano; C Ganoza; J R Lama; J Sanchez; M J McElrath
Journal:  Mucosal Immunol       Date:  2015-10-28       Impact factor: 7.313
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  1 in total

1.  Accuracy of Pathologic Diagnosis in Patients With Lymphoma and Survival: A Prospective Analysis From Botswana.

Authors:  Fallon E Chipidza; Mukendi K A Kayembe; Isaac Nkele; Jason A Efstathiou; Bruce A Chabner; Jeremy Abramson; Scott L Dryden-Peterson; Aliyah R Sohani
Journal:  JCO Glob Oncol       Date:  2021-09
  1 in total

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