Literature DB >> 29412682

Pentaketide Ansamycin Microansamycins A-I from Micromonospora sp. Reveal Diverse Post-PKS Modifications.

Jianxiong Wang1, Wen Li2, Haoxin Wang2, Chunhua Lu1.   

Abstract

Overexpression of the pathway-specific positive regulator gene mas13 activated the cryptic gene cluster mas, resulting in the isolation of nine novel pentaketide ansamycins, namely, microansamycins A-I (1-9). These results not only revealed a biosynthetic gene cluster of pentaketide ansamycins for the first time but also presented an unprecedented scenario of diverse post-PKS modifications in ansamycin biosynthesis.

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Year:  2018        PMID： 29412682     DOI： 10.1021/acs.orglett.7b04018

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  7 in total

1.  Microcella flavibacter sp. nov., isolated from marine sediment, and reclassification of Chryseoglobus frigidaquae, Chryseoglobus indicus, and Yonghaparkia alkaliphila as Microcella frigidaquae comb. nov., Microcella indica nom. nov., and Microcella alkalica nom. nov.

Authors:  Fuquan Xie; Shengxiang Pei; Xiaoyun Huang; Lina Wang; Jinyan Kou; Gaiyun Zhang
Journal:  Antonie Van Leeuwenhoek       Date:  2021-10-10       Impact factor: 2.271

Review 2.  The genus Micromonospora as a model microorganism for bioactive natural product discovery.

Authors:  Mohamed S Hifnawy; Mohamed M Fouda; Ahmed M Sayed; Rabab Mohammed; Hossam M Hassan; Sameh F AbouZid; Mostafa E Rateb; Alexander Keller; Martina Adamek; Nadine Ziemert; Usama Ramadan Abdelmohsen
Journal:  RSC Adv       Date:  2020-06-08       Impact factor: 4.036

3.  8-Deoxy-Rifamycin Derivatives from Amycolatopsis mediterranei S699 ΔrifT Strain.

Authors:  Feng Ye; Yanrong Shi; Shengliang Zhao; Zhiying Li; Haoxin Wang; Chunhua Lu; Yuemao Shen
Journal:  Biomolecules       Date:  2020-09-02

4.  Polyene-Producing Streptomyces spp. From the Fungus-Growing Termite Macrotermes barneyi Exhibit High Inhibitory Activity Against the Antagonistic Fungus Xylaria.

Authors:  Jingjing Li; Moli Sang; Yutong Jiang; Jianhua Wei; Yulong Shen; Qihong Huang; Yaoyao Li; Jinfeng Ni
Journal:  Front Microbiol       Date:  2021-04-01       Impact factor: 5.640

5.  Subtercola endophyticus sp. nov., a cold-adapted bacterium isolated from Abies koreana.

Authors:  Lingmin Jiang; Yuxin Peng; Jiyoon Seo; Doeun Jeon; Mi Gyeong Jo; Ju Huck Lee; Jae Cheol Jeong; Cha Young Kim; Hyeong Cheol Park; Jiyoung Lee
Journal:  Sci Rep       Date:  2022-07-15       Impact factor: 4.996

6.  Bioactive potentiality of secondary metabolites from endophytic bacteria against SARS-COV-2: An in-silico approach.

Authors:  Yasmin Akter; Rocktim Barua; Md Nasir Uddin; Abul Fazal Muhammad Sanaullah; Lolo Wal Marzan
Journal:  PLoS One       Date:  2022-08-04       Impact factor: 3.752

7.  Rifamycin W Analogues from Amycolatopsis mediterranei S699 Δrif-orf5 Strain.

Authors:  Yanrong Shi; Feng Ye; Yuliang Song; Xiaochun Zhang; Chunhua Lu; Yuemao Shen
Journal:  Biomolecules       Date:  2021-06-22
  7 in total

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