Literature DB >> 29411907

A Synthetic Approach for the Rapid Preparation of BODIPY Conjugates and their use in Imaging of Cellular Drug Uptake and Distribution.

Sona Krajcovicova1, Jarmila Stankova2, Petr Dzubak2, Marian Hajduch2, Miroslav Soural1, Milan Urban2.   

Abstract

A solid-phase synthetic (SPS) method was developed for the preparation of BODIPY-labeled bioactive compounds that allows for fast and simple synthesis of conjugates for use in fluorescent microscopy. The approach was used to visualize cellular uptake and distribution of cytotoxic triterpenes in cancer cells.
© 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  cytotoxicity; dyes/pigments; fluorescence microscopy; solid-phase synthesis; terpenoids

Mesh：

Substances：

Year:  2018        PMID： 29411907     DOI： 10.1002/chem.201706093

Source DB:  PubMed          Journal:  Chemistry        ISSN： 0947-6539            Impact factor:   5.236


  6 in total

1.  Polymer-supported synthesis of N-substituted anthranilates as the building blocks for preparation of N-arylated 3-hydroxyquinolin-4(1H)-ones.

Authors:  Soňa Krajčovičová; Jan Hlaváč; Kristýna Vychodilová
Journal:  RSC Adv       Date:  2021-03-02       Impact factor: 3.361

2.  Cytotoxicity of Amino-BODIPY Modulated via Conjugation with 2-Phenyl-3-Hydroxy-4(1H)-Quinolinones.

Authors:  Martin Porubský; Kristýna Vychodilová; David Milićević; Miloš Buděšinský; Jarmila Stanková; Petr Džubák; Marián Hajdúch; Jan Hlaváč
Journal:  ChemistryOpen       Date:  2021-08-23       Impact factor: 2.630

Review 3.  BODIPY Conjugates as Functional Compounds for Medical Diagnostics and Treatment.

Authors:  Elena Antina; Natalia Bumagina; Yuriy Marfin; Galina Guseva; Liliya Nikitina; Dmitry Sbytov; Felix Telegin
Journal:  Molecules       Date:  2022-02-18       Impact factor: 4.411

Review 4.  Semisynthetic Derivatives of Pentacyclic Triterpenes Bearing Heterocyclic Moieties with Therapeutic Potential.

Authors:  Gabriela Nistor; Cristina Trandafirescu; Alexandra Prodea; Andreea Milan; Andreea Cristea; Roxana Ghiulai; Roxana Racoviceanu; Alexandra Mioc; Marius Mioc; Viviana Ivan; Codruța Șoica
Journal:  Molecules       Date:  2022-10-03       Impact factor: 4.927

5.  Solid-phase fluorescent BODIPY-peptide synthesis via in situ dipyrrin construction.

Authors:  Yue Wu; Wing-Sze Tam; Ho-Fai Chau; Simranjeet Kaur; Waygen Thor; Wei Shen Aik; Wai-Lun Chan; Markus Zweckstetter; Ka-Leung Wong
Journal:  Chem Sci       Date:  2020-09-24       Impact factor: 9.825

6.  BODIPY as electron withdrawing group for the activation of double bonds in asymmetric cycloaddition reactions.

Authors:  Andrea Guerrero-Corella; Juan Asenjo-Pascual; Tushar Janardan Pawar; Sergio Díaz-Tendero; Ana Martín-Sómer; Clarisa Villegas Gómez; José L Belmonte-Vázquez; Diana E Ramírez-Ornelas; Eduardo Peña-Cabrera; Alberto Fraile; David Cruz Cruz; José Alemán
Journal:  Chem Sci       Date:  2019-03-20       Impact factor: 9.825
  6 in total

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