| Literature DB >> 29410784 |
Yan Wang1, Xinguang Chen1, Jacob Ball1, Xiaoming Li2, Yuejiao Zhou3, Zhiyong Shen3.
Abstract
BACKGROUND: Alcohol use remains a significant challenge for treating people living with HIV (people living with HIV). We aimed to examine current use and retrospective self-reported changes in drinking behavior after HIV+ diagnosis in people living with HIV.Entities:
Keywords: HIV in China; HIV test; alcohol use; behavior change; people living with HIV
Year: 2018 PMID: 29410784 PMCID: PMC5794042 DOI: 10.1177/2050312118755783
Source DB: PubMed Journal: SAGE Open Med ISSN: 2050-3121
Characteristics of the study sample by gender, n (%).
| Characteristics | Male (n = 1861) | Female (n = 1103) | Total (n = 2964) |
|---|---|---|---|
| Age in years | |||
| Mean (SD) | 44.2 (12.9) | 39.5 (12.2) | 42.5 (12.8) |
| <35 | 494 (26.5) | 503 (45.6) | 997 (33.6) |
| 35–44 | 687 (36.9) | 315 (28.6) | 1002 (33.8) |
| ≥45 | 680 (36.5) | 285 (25.8) | 965 (32.6) |
| Ethnicity | |||
| Han | 1367 (73.6) | 728 (66.1) | 2095 (70.8) |
| Zhuang | 449 (24.2) | 316 (28.7) | 765 (25.8) |
| Other | 42 (2.3) | 58 (5.3) | 100 (3.4) |
| Years of education | |||
| 0–6 | 860 (46.3) | 508 (46.2) | 1368 (46.3) |
| 7–9 | 770 (41.5) | 463 (42.1) | 1233 (41.7) |
| 10–12 | 171 (9.2) | 102 (9.3) | 273 (9.2) |
| >12 | 55 (3.0) | 27 (2.4) | 82 (2.8) |
| Average monthly household income | |||
| <¥1000 | 996 (54.1) | 564 (51.6) | 1560 (53.2) |
| ≥¥1000 | 845 (45.9) | 530 (48.4) | 1375 (46.8) |
| If employed | |||
| Yes | 1325 (71.5) | 834 (76.0) | 2159 (73.1) |
| No | 528 (28.5) | 264 (24.0) | 792 (26.8) |
| Marital status | |||
| Never married | 336 (18.5) | 65 (6.0) | 401 (13.9) |
| Married | 1172 (64.6) | 753 (69.6) | 1925 (66.5) |
| Divorced/separated | 164 (9.1) | 89 (8.2) | 253 (8.7) |
| Widowed | 141 (7.8) | 176 (16.2) | 316 (10.9) |
| Sexual minority | |||
| No | 784 (88.9) | 523 (87.5) | 1307(88.3) |
| Yes | 98 (11.1) | 75 (12.5) | 173(11.7) |
| CD4 count | |||
| Mean (SD) | 328 (226) | 376 (205) | 346 (219) |
| <200 | 533 (30.2) | 200 (18.7) | 733(25.8) |
| 200–349 | 531 (30.1) | 312 (29.1) | 843 (29.7) |
| 350–499 | 396 (22.4) | 305 (28.4) | 701 (24.7) |
| ≥500 | 307 (17.4) | 255 (23.8) | 563 (19.8) |
| On ART | |||
| Yes | 1307 (70.5) | 825 (75.0) | 2138 (72.2) |
| No | 546 (29.5) | 275 (25.0) | 824(27.8) |
| Time since HIV+ diagnosis (years) | |||
| ≤1 | 409 (22.2) | 215 (19.6) | 624 (21.2) |
| >1 | 1437 (77.8) | 882 (80.4) | 2319 (78.8) |
SD: standard deviation; ART: antiretroviral therapy.
Sample sizes are not equivalent for all variables because of missing data or legitimate skip.
¥1 = US$0.16.
Gender difference: **p < 0.01.
Figure 1.Patterns of alcohol consumption: (a) frequency of alcohol use, (b) amount of alcohol consumed per day on drinking days, (c) prevalence of binge drinking and hazardous drinking, and (d) frequency of binge drinking.
Binge drinking was defined as consuming six drinks for men and four drinks for women on a single occasion. Hazardous drinking was defined as having engaged in binge drinking one or more times per week.
Changes in drinking behavior after receiving HIV+ diagnosis and their associations with sample characteristics.
| Characteristics | Started/increased, n (%) | Reduced, n (%) | Quit, n (%) |
|---|---|---|---|
| Overall | 31 (2.5) | 564 (45.4) | 242 (19.5) |
| Age in years | |||
| <35 | 17 (54.8) | 217 (38.5) | 72 (29.8) |
| 35–44 | 9 (29.0) | 199 (35.3) | 68 (28.1) |
| ≥45 | 5 (16.1) | 148 (26.2) | 102 (42.1) |
| Gender | |||
| Male | 21 (67.7)[ | 488 (86.5) | 191 (78.9) |
| Female | 10 (32.3) | 76 (13.5) | 51 (21.1) |
| Ethnicity | |||
| Han | 24 (77.4) | 381 (67.7) | 170 (70.2) |
| Zhuang | 4 (12.9) | 167 (29.7) | 65 (26.9) |
| Other | 3 (9.7) | 15 (2.7) | 7 (2.9) |
| Years of education | |||
| 0–6 | 16 (51.6) | 206 (36.5) | 116 (48.1) |
| 7–9 | 12 (38.7) | 265 (47.0) | 78 (32.4) |
| 10–12 | 3 (9.7) | 69 (12.2) | 37 (15.4) |
| >12 | 0 (0) | 24 (4.3) | 10 (4.1) |
| Average monthly household income | |||
| <¥1000 | 9 (29.0) | 295 (52.4) | 95 (39.8) |
| ≥¥1000 | 22 (71.0) | 268 (47.6) | 144 (60.2) |
| Marital status | |||
| Never married | 8 (25.8) | 107 (19.4) | 37 (15.3) |
| Married | 16 (51.6) | 354 (64.0) | 162 (66.9) |
| Divorced/separated | 5 (416.1) | 62 (11.2) | 15 (6.2) |
| Widowed | 2 (6.5) | 30 (5.4) | 28 (11.6) |
| If employed | |||
| Yes | 26 (86.7) | 419 (74.4) | 160 (66.4) |
| No | 4 (13.3) | 144 (25.6) | 81 (33.6) |
| Sexual minority | |||
| No | 14 (93.3) | 282 (91.6) | 98 (89.9) |
| Yes | 1 (6.7) | 26 (8.4) | 11 (10.1) |
| On ART | |||
| Yes | 20 (64.5) | 417 (74.1) | 181 (75.1) |
| No | 11 (35.5) | 146 (25.9) | 60 (24.9) |
| Time since HIV+ diagnosis (years) | |||
| ≤1 | 4 (12.9) | 92 (16.5) | 85 (35.3) |
| >1 | 27 (87.1) | 465 (83.5) | 156 (64.7) |
ART: antiretroviral therapy.
Sample sizes are not equivalent for all variables because of missing data or legitimate skip.
Fisher’s exact test was used.
p < 0.05; **p < 0.01.
Logistic regression results of changes in drinking behavior after receiving HIV+ diagnosis.
| Characteristics | Started/increased, OR (95% CIs) | Reduced, OR (95% CIs) | Quit, OR (95% CIs) |
|---|---|---|---|
| Age in years | |||
| <35 | 1.27(0.95, 1.71) | 0.62(0.41, 0.93) | |
| 35–44 | 1.28(0.95, 1.72) | 0.67(0.46, 0.98) | |
| ≥45 | – | – | |
| Gender | |||
| Male | 0.39(0.18, 0.86) | 0.54(0.36, 0.81) | |
| Female | – | – | |
| Ethnicity | |||
| Han | 0.30(0.08, 1.09) | 0.96(0.46, 2.01) | |
| Zhuang | 0.13(0.03, 0.62) | 1.24(0.58, 2.65) | |
| Other | – | – | |
| Years of education | |||
| 0–6 | 0.52 (0.28, 0.99) | 0.99(0.45, 2.15) | |
| 7–9 | 0.76 (0.40, 1.42) | 0.57(0.26, 1.25) | |
| 10–12 | 0.76 (0.38, 1.52) | 1.01(0.44, 2.34) | |
| >12 | – | – | |
| Average monthly household income | |||
| <¥1000 | 0.45(0.20, 0.99) | 1.41(1.11, 1.79) | 0.62(0.45, 0.85) |
| ≥¥1000 | – | – | – |
| Marital status | |||
| Never married | 0.60(0.31, 1.15) | ||
| Married | 0.74(0.44, 1.26) | ||
| Divorced/separated | 0.43(0.20, 0.92) | ||
| Widowed | – | ||
| If employed | |||
| Yes | 1.52(1.09, 2.13) | ||
| No | – | ||
| On ART | |||
| Yes | 1.69(1.30, 2.18) | 1.77(1.24, 2.53) | |
| No | – | – | |
| Time since HIV+ diagnosis (years) | |||
| ≤1 | 0.68 (0.51, 0.92) | 2.50(1.78, 3.52) | |
| >1 | – | – | |
OR: odds ratio; CI: confidence interval; ART: antiretroviral therapy.
Each drinking behavior change type was used as outcome variable, respectively. Sample characteristic variables were used as predictors. Multivariate logistic regression was used to include all sample characteristics. Only variables that showed significant association in the univariate analysis in Table 2 were included in the multivariate model here.
*p < 0.05; **p < 0.01.