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Literature DB >> 29410362

Tetracaine derivatives for catecholaminergic polymorphic ventricular tachycardia: New drugs for correction of diastolic Ca²⁺ leak?

Héctor H Valdivia¹, Carmen R Valdivia².

Abstract

Entities: CellLine Chemical Disease Gene Mutation Species

Mesh：

Substances：

Year: 2018 PMID： 29410362 PMCID： PMC5906042 DOI： 10.1016/j.hrthm.2018.01.022

Source DB: PubMed Journal: Heart Rhythm ISSN： 1547-5271 Impact factor: 6.343

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11 in total

1. A Precision Medicine Approach to the Rescue of Function on Malignant Calmodulinopathic Long-QT Syndrome.

Authors: Worawan B Limpitikul; Ivy E Dick; David J Tester; Nicole J Boczek; Pattraranee Limphong; Wanjun Yang; Myoung Hyun Choi; Jennifer Babich; Deborah DiSilvestre; Ronald J Kanter; Gordon F Tomaselli; Michael J Ackerman; David T Yue
Journal: Circ Res Date: 2016-10-20 Impact factor: 17.367

2. Dissociation of calmodulin from cardiac ryanodine receptor causes aberrant Ca(2+) release in heart failure.

Authors: Makoto Ono; Masafumi Yano; Akihiro Hino; Takeshi Suetomi; Xiaojuan Xu; Takehisa Susa; Hitoshi Uchinoumi; Hiroki Tateishi; Tetsuro Oda; Shinichi Okuda; Masahiro Doi; Shigeki Kobayashi; Takeshi Yamamoto; Noritaka Koseki; Hiroyuki Kyushiki; Noriaki Ikemoto; Masunori Matsuzaki
Journal: Cardiovasc Res Date: 2010-04-13 Impact factor: 10.787

3. Carvedilol and its new analogs suppress arrhythmogenic store overload-induced Ca2+ release.

Authors: Qiang Zhou; Jianmin Xiao; Dawei Jiang; Ruiwu Wang; Kannan Vembaiyan; Aixia Wang; Chris D Smith; Cuihong Xie; Wenqian Chen; Jingqun Zhang; Xixi Tian; Peter P Jones; Xiaowei Zhong; Ang Guo; Haiyan Chen; Lin Zhang; Weizhong Zhu; Dongmei Yang; Xiaodong Li; Ju Chen; Anne M Gillis; Henry J Duff; Heping Cheng; Arthur M Feldman; Long-Sheng Song; Michael Fill; Thomas G Back; S R Wayne Chen
Journal: Nat Med Date: 2011-07-10 Impact factor: 53.440

4. Short communication: flecainide exerts an antiarrhythmic effect in a mouse model of catecholaminergic polymorphic ventricular tachycardia by increasing the threshold for triggered activity.

Authors: Nian Liu; Marco Denegri; Yanfei Ruan; José Everardo Avelino-Cruz; Andrea Perissi; Sara Negri; Carlo Napolitano; William A Coetzee; Penelope A Boyden; Silvia G Priori
Journal: Circ Res Date: 2011-06-16 Impact factor: 17.367

5. Defective calmodulin binding to the cardiac ryanodine receptor plays a key role in CPVT-associated channel dysfunction.

Authors: Xiaojuan Xu; Masafumi Yano; Hitoshi Uchinoumi; Akihiro Hino; Takeshi Suetomi; Makoto Ono; Hiroki Tateishi; Tetsuro Oda; Shinichi Okuda; Masahiro Doi; Shigeki Kobayashi; Takeshi Yamamoto; Yasuhiro Ikeda; Noriaki Ikemoto; Masunori Matsuzaki
Journal: Biochem Biophys Res Commun Date: 2010-03-10 Impact factor: 3.575

6. Defective domain-domain interactions within the ryanodine receptor as a critical cause of diastolic Ca2+ leak in failing hearts.

Authors: Hiroki Tateishi; Masafumi Yano; Mamoru Mochizuki; Takeshi Suetomi; Makoto Ono; Xiaojuan Xu; Hitoshi Uchinoumi; Shinichi Okuda; Tetsuro Oda; Shigeki Kobayashi; Takeshi Yamamoto; Yasuhiro Ikeda; Tomoko Ohkusa; Noriaki Ikemoto; Masunori Matsuzaki
Journal: Cardiovasc Res Date: 2008-11-07 Impact factor: 10.787

7. Ryanodine receptor mutations associated with stress-induced ventricular tachycardia mediate increased calcium release in stimulated cardiomyocytes.

Authors: Christopher H George; Gemma V Higgs; F Anthony Lai
Journal: Circ Res Date: 2003-08-14 Impact factor: 17.367

Tetracaine derivatives for catecholaminergic polymorphic ventricular tachycardia: New drugs for correction of diastolic Ca²⁺ leak?

1. A Precision Medicine Approach to the Rescue of Function on Malignant Calmodulinopathic Long-QT Syndrome.

2. Dissociation of calmodulin from cardiac ryanodine receptor causes aberrant Ca(2+) release in heart failure.

3. Carvedilol and its new analogs suppress arrhythmogenic store overload-induced Ca2+ release.

4. Short communication: flecainide exerts an antiarrhythmic effect in a mouse model of catecholaminergic polymorphic ventricular tachycardia by increasing the threshold for triggered activity.

5. Defective calmodulin binding to the cardiac ryanodine receptor plays a key role in CPVT-associated channel dysfunction.

6. Defective domain-domain interactions within the ryanodine receptor as a critical cause of diastolic Ca2+ leak in failing hearts.

7. Ryanodine receptor mutations associated with stress-induced ventricular tachycardia mediate increased calcium release in stimulated cardiomyocytes.

8. EL20, a potent antiarrhythmic compound, selectively inhibits calmodulin-deficient ryanodine receptor type 2.

9. Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans.

10. Cardiac myocyte Z-line calmodulin is mainly RyR2-bound, and reduction is arrhythmogenic and occurs in heart failure.

Review 1. Therapeutic Approaches of Ryanodine Receptor-Associated Heart Diseases.