Eric S Nussbaum1, Chris Hilton2, Archie Defillo3, William McDonald4, Theodore Passe5, Kevin M Kallmes6, Leslie A Nussbaum1. 1. Department of Neurosurgery, United Hospital, Allina Healthcare System, St. Paul, MN, United States; Minnesota Neurovascular & Skull Base Surgery, Minneapolis, MN, United States. 2. Department of Otolaryngology, Regions Hospital, St. Paul, MN, United States. 3. Minnesota Neurovascular & Skull Base Surgery, Minneapolis, MN, United States. 4. Department of Pathology, Allina Healthcare System, St. Paul, MN, United States. 5. Neuroradiology, St. Paul Radiology, St. Paul, MN, United States. 6. Duke University Law School, Durham, NC, United States. Electronic address: kevin.kallmes@duke.edu.
Abstract
BACKGROUND: Calcifying pseudoneoplasm of the neuraxis (CAPNON) is a very rare tumor with fewer than 70 cases reported in the literature. In general, this tumor occurs intracranially either within the brain parenchyma or in an extra-axial location, but it has also been described within the spine as an extra-axial lesion. CASE DESCRIPTION: We describe an unusual case of intracranial-extradural CAPNON involving the mastoid region. This may be only the second such case reported in the literature, as one patient with CAPNON has been reported involving the sinonasal region. Our patient was managed with surgical resection through a translabyrinthine approach with good early result. CONCLUSIONS: We describe an unusual case of extradural CAPNON involving the mastoid bone. It appears that when located extradurally, this tumor may have a predilection for the bony sinuses. This little-known, generally benign entity can mimic more common lesions such as meningiomas, and should be considered in the differential diagnosis of skull base tumors, particularly when associated with heavy calcification.
BACKGROUND: Calcifying pseudoneoplasm of the neuraxis (CAPNON) is a very rare tumor with fewer than 70 cases reported in the literature. In general, this tumor occurs intracranially either within the brain parenchyma or in an extra-axial location, but it has also been described within the spine as an extra-axial lesion. CASE DESCRIPTION: We describe an unusual case of intracranial-extradural CAPNON involving the mastoid region. This may be only the second such case reported in the literature, as one patient with CAPNON has been reported involving the sinonasal region. Our patient was managed with surgical resection through a translabyrinthine approach with good early result. CONCLUSIONS: We describe an unusual case of extradural CAPNON involving the mastoid bone. It appears that when located extradurally, this tumor may have a predilection for the bony sinuses. This little-known, generally benign entity can mimic more common lesions such as meningiomas, and should be considered in the differential diagnosis of skull base tumors, particularly when associated with heavy calcification.
Authors: J C Benson; J Trejo-Lopez; J Boland-Froemming; B Pollock; C H Hunt; J T Wald Journal: AJNR Am J Neuroradiol Date: 2021-07-22 Impact factor: 4.966
Authors: Colin A Dallimore; Mica Quelle; Likowsky L Désir; Sunder Sham; Manju Harshan; Samuel J Wahl; Avraham Zlochower; Robert R Goodman; David J Langer; Randy S D'Amico Journal: Cureus Date: 2022-01-24