Literature DB >> 29408054

Paradoxical accentuation of motivation following accumbens-pallidum disconnection.

Stephen E Chang1, Travis P Todd2, Kyle S Smith2.   

Abstract

The nucleus accumbens (NAc) and ventral pallidum (VP) are reciprocally connected, and activity within this circuit is thought to promote reward learning. Inconsistent with this notion, we find that disconnecting NAc medial shell and VP greatly enhances the attribution of value to a cue that is paired with reward. This result suggests that medial NAc shell and VP are both needed for attributing value to cues yet can also oppose one-another's functional contribution.
Copyright © 2018 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Nucleus accumbens; Sign-tracking; Ventral pallidum

Mesh：

Year:  2018        PMID： 29408054      PMCID： PMC5864546          DOI： 10.1016/j.nlm.2018.02.001

Source DB:  PubMed          Journal:  Neurobiol Learn Mem        ISSN： 1074-7427            Impact factor:   2.877


  34 in total

1.  Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand.

Authors:  Blaine N Armbruster; Xiang Li; Mark H Pausch; Stefan Herlitze; Bryan L Roth
Journal:  Proc Natl Acad Sci U S A       Date:  2007-03-02       Impact factor: 11.205

2.  Optogenetic activation of GABAergic neurons in the nucleus accumbens decreases the activity of the ventral pallidum and the expression of cocaine-context-associated memory.

Authors:  Li Wang; Minjie Shen; Yongchun Yu; Yezheng Tao; Ping Zheng; Feifei Wang; Lan Ma
Journal:  Int J Neuropsychopharmacol       Date:  2014-01-23       Impact factor: 5.176

3.  Afferent and efferent connections of the medial preoptic area in the rat: a WGA-HRP study.

Authors:  T Chiba; Y Murata
Journal:  Brain Res Bull       Date:  1985-03       Impact factor: 4.077

4.  Distribution of glutamate decarboxylase, choline acetyl-transferase and aromatic amino acid decarboxylase in the basal ganglia of normal and operated rats. Evidence for striatopallidal, striatoentopeduncular and striatonigral GABAergic fibres.

Authors:  F Fonnum; Z Gottesfeld; I Grofova
Journal:  Brain Res       Date:  1978-03-17       Impact factor: 3.252

5.  A topographically organized gamma-aminobutyric acid projection from the ventral pallidum to the nucleus accumbens in the rat.

Authors:  L Churchill; P W Kalivas
Journal:  J Comp Neurol       Date:  1994-07-22       Impact factor: 3.215

Review 6.  Ventral pallidum roles in reward and motivation.

Authors:  Kyle S Smith; Amy J Tindell; J Wayne Aldridge; Kent C Berridge
Journal:  Behav Brain Res       Date:  2008-10-08       Impact factor: 3.332

7.  The ventral striato-pallidal pathway mediates the effect of predictive learning on choice between goal-directed actions.

Authors:  Beatrice K Leung; Bernard W Balleine
Journal:  J Neurosci       Date:  2013-08-21       Impact factor: 6.167

8.  Effects of nucleus accumbens core and shell lesions on autoshaped lever-pressing.

Authors:  Stephen E Chang; Peter C Holland
Journal:  Behav Brain Res       Date:  2013-08-06       Impact factor: 3.332

9.  Neurobiological Basis of Individual Variation in Stimulus-Reward Learning.

Authors:  Shelly B Flagel; Terry E Robinson
Journal:  Curr Opin Behav Sci       Date:  2017-01-05

10.  Evidence for the coexistence of glutamate decarboxylase and Met-enkephalin immunoreactivities in axon terminals of rat ventral pallidum.

Authors:  D S Zahm; L Zaborszky; V E Alones; L Heimer
Journal:  Brain Res       Date:  1985-01-28       Impact factor: 3.252
View more
  8 in total

1.  Chemogenetic Manipulations of Ventral Tegmental Area Dopamine Neurons Reveal Multifaceted Roles in Cocaine Abuse.

Authors:  Stephen V Mahler; Zachary D Brodnik; Brittney M Cox; William C Buchta; Brandon S Bentzley; Julian Quintanilla; Zackary A Cope; Edwin C Lin; Matthew D Riedy; Michael D Scofield; Justin Messinger; Christina M Ruiz; Arthur C Riegel; Rodrigo A España; Gary Aston-Jones
Journal:  J Neurosci       Date:  2018-11-16       Impact factor: 6.167

2.  Chronic chemogenetic manipulation of ventral pallidum targeted neurons in male rats fed an obesogenic diet.

Authors:  Wilder T Doucette; Elizabeth B Smedley; Metztli Ruiz-Jaquez; Jibran Y Khokhar; Kyle S Smith
Journal:  Brain Res       Date:  2022-03-18       Impact factor: 3.610

3.  Ventral pallidum is essential for cocaine relapse after voluntary abstinence in rats.

Authors:  Mitchell R Farrell; Christina M Ruiz; Erik Castillo; Lauren Faget; Christine Khanbijian; Siyu Liu; Hannah Schoch; Gerardo Rojas; Michelle Y Huerta; Thomas S Hnasko; Stephen V Mahler
Journal:  Neuropsychopharmacology       Date:  2019-09-02       Impact factor: 7.853

4.  Ventral pallidal encoding of reward-seeking behavior depends on the underlying associative structure.

Authors:  Jocelyn M Richard; Nakura Stout; Deanna Acs; Patricia H Janak
Journal:  Elife       Date:  2018-03-22       Impact factor: 8.140

5.  Sign-tracking behavior is sensitive to outcome devaluation in a devaluation context-dependent manner: implications for analyzing habitual behavior.

Authors:  Kenneth A Amaya; Jeffrey J Stott; Kyle S Smith
Journal:  Learn Mem       Date:  2020-03-16       Impact factor: 2.460

6.  Ventral arkypallidal neurons inhibit accumbal firing to promote reward consumption.

Authors:  Yvan M Vachez; Jessica R Tooley; Kavitha Abiraman; Bridget Matikainen-Ankney; Eric Casey; Tom Earnest; Leana M Ramos; Hanna Silberberg; Elizabeth Godynyuk; Olivia Uddin; Lauren Marconi; Claire E Le Pichon; Meaghan C Creed
Journal:  Nat Neurosci       Date:  2021-01-25       Impact factor: 24.884

7.  Distinct role of nucleus accumbens D2-MSN projections to ventral pallidum in different phases of motivated behavior.

Authors:  Carina Soares-Cunha; Ana Verónica Domingues; Raquel Correia; Bárbara Coimbra; Natacha Vieitas-Gaspar; Nivaldo A P de Vasconcelos; Luísa Pinto; Nuno Sousa; Ana João Rodrigues
Journal:  Cell Rep       Date:  2022-02-15       Impact factor: 9.423

8.  Ventral pallidum encodes relative reward value earlier and more robustly than nucleus accumbens.

Authors:  David Ottenheimer; Jocelyn M Richard; Patricia H Janak
Journal:  Nat Commun       Date:  2018-10-19       Impact factor: 14.919
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.