M Härter1,2, A Jansen3,4, M Berger5, H Baumeister6, T Bschor7,8, T Harfst4, M Hautzinger9, L Kriston3, C Kühner10, H Schauenburg11, S G Schorr12, F Schneider13,14, R Meister3. 1. Institut und Poliklinik für Medizinische Psychologie, Universitätsklinikum Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Deutschland. m.haerter@uke.de. 2. Klinik für Psychiatrie und Psychotherapie, Zentralinstitut für Seelische Gesundheit Mannheim, Mannheim, Deutschland. m.haerter@uke.de. 3. Institut und Poliklinik für Medizinische Psychologie, Universitätsklinikum Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Deutschland. 4. Bundespsychotherapeutenkammer (BPtK), Berlin, Deutschland. 5. Klinik für Psychiatrie und Psychotherapie, Universitätsklinikum Freiburg, Freiburg, Deutschland. 6. Abteilung Klinische Psychologie und Psychotherapie, Universität Ulm, Ulm, Deutschland. 7. Abteilung für Psychiatrie, Schlosspark-Klinik Berlin, Berlin, Deutschland. 8. Klinik und Poliklinik für Psychiatrie und Psychotherapie, Technische Universität Dresden, Dresden, Deutschland. 9. Fachbereich für Psychologie, Klinische Psychologie und Psychotherapie, Eberhard Karls Universität Tübingen, Tübingen, Deutschland. 10. Klinik für Psychiatrie und Psychotherapie, Zentralinstitut für Seelische Gesundheit Mannheim, Mannheim, Deutschland. 11. Klinik für Allgemeine Innere Medizin und Psychosomatik, Universitätsklinikum Heidelberg, Heidelberg, Deutschland. 12. Ärztliches Zentrum für Qualität in der Medizin (ÄZQ), Berlin, Deutschland. 13. Klinik für Psychiatrie, Psychotherapie und Psychosomatik, Uniklinik RWTH Aachen, Aachen, Deutschland. 14. Institut für Neurowissenschaften und Medizin (INM 10), Forschungszentrum Jülich, Jülich, Deutschland.
Abstract
BACKGROUND: Psychotherapy has been shown to be an effective treatment option for depressive disorders; however, its effectiveness varies depending on patient and therapist characteristics and the individual form of the depressive disorder. OBJECTIVES: The aim of this article is to present the current evidence for psychotherapeutic antidepressive treatments for patients with chronic and treatment-resistant depression as well as for patients with mental and somatic comorbidities. MATERIAL AND METHODS: During the revision of the currently valid German S3- and National Disease Management Guideline (NDMG) on unipolar depression published in 2015, a comprehensive and systematic evidence search including psychotherapy for specific patient groups was conducted. The results of this search along with a systematic update are summarized. RESULTS: Psychotherapy has been shown to be effective in reducing depressive symptoms in patients suffering from chronic and treatment-resistant depression and in patients with mental and somatic comorbidities. The evidence is insufficient particularly for patients with mental comorbidities. CONCLUSION: Based on the current evidence and clinical expertise the NDMG recommends psychotherapy alone or in combination with pharmacotherapy to treat most of these depressive patient groups. Evidence gaps were identified, which highlight the need for further research.
BACKGROUND: Psychotherapy has been shown to be an effective treatment option for depressive disorders; however, its effectiveness varies depending on patient and therapist characteristics and the individual form of the depressive disorder. OBJECTIVES: The aim of this article is to present the current evidence for psychotherapeutic antidepressive treatments for patients with chronic and treatment-resistant depression as well as for patients with mental and somatic comorbidities. MATERIAL AND METHODS: During the revision of the currently valid German S3- and National Disease Management Guideline (NDMG) on unipolar depression published in 2015, a comprehensive and systematic evidence search including psychotherapy for specific patient groups was conducted. The results of this search along with a systematic update are summarized. RESULTS: Psychotherapy has been shown to be effective in reducing depressive symptoms in patients suffering from chronic and treatment-resistant depression and in patients with mental and somatic comorbidities. The evidence is insufficient particularly for patients with mental comorbidities. CONCLUSION: Based on the current evidence and clinical expertise the NDMG recommends psychotherapy alone or in combination with pharmacotherapy to treat most of these depressivepatient groups. Evidence gaps were identified, which highlight the need for further research.
Authors: An Pan; Michel Lucas; Qi Sun; Rob M van Dam; Oscar H Franco; Walter C Willett; JoAnn E Manson; Kathryn M Rexrode; Alberto Ascherio; Frank B Hu Journal: Arch Gen Psychiatry Date: 2011-01
Authors: R Meister; A Jansen; M Berger; H Baumeister; T Bschor; T Harfst; M Hautzinger; L Kriston; C Kühner; H Schauenburg; S G Schorr; F Schneider; M Härter Journal: Nervenarzt Date: 2018-03 Impact factor: 1.214
Authors: Elisabeth Schramm; Levente Kriston; Ingo Zobel; Josef Bailer; Katrin Wambach; Matthias Backenstrass; Jan Philipp Klein; Dieter Schoepf; Knut Schnell; Antje Gumz; Paul Bausch; Thomas Fangmeier; Ramona Meister; Mathias Berger; Martin Hautzinger; Martin Härter Journal: JAMA Psychiatry Date: 2017-03-01 Impact factor: 21.596