Literature DB >> 29404401

miRNA-convergent gene fusions.

Carlos Rovira1.   

Abstract

In a recent study published in Nature Communications, we showed that intron-encoded microRNA genes (miRNA) are frequent partners of fusion genes in the cancer genome. Analyzed from a functional rather than structural perspective, these rearrangements represent a new class of fusions we called "miRNA-convergent fusions".

Entities:  

Keywords:  cancer; gene fusions; genome aberrations; microRNA

Year:  2017        PMID： 29404401      PMCID： PMC5791861          DOI： 10.1080/23723556.2017.1406433

Source DB:  PubMed          Journal:  Mol Cell Oncol        ISSN： 2372-3556


  9 in total

1.  Discovery of recurrent t(6;7)(p25.3;q32.3) translocations in ALK-negative anaplastic large cell lymphomas by massively parallel genomic sequencing.

Authors:  Andrew L Feldman; Ahmet Dogan; David I Smith; Mark E Law; Stephen M Ansell; Sarah H Johnson; Julie C Porcher; Nazan Ozsan; Eric D Wieben; Bruce W Eckloff; George Vasmatzis
Journal:  Blood       Date:  2010-10-28       Impact factor: 22.113

2.  T(3;7)(q27;q32) fuses BCL6 to a non-coding region at FRA7H near miR-29.

Authors:  B Schneider; S Nagel; M Kaufmann; S Winkelmann; J Bode; H G Drexler; R A F MacLeod
Journal:  Leukemia       Date:  2007-11-08       Impact factor: 11.528

3.  MicroRNA-125b-1 and BLID upregulation resulting from a novel IGH translocation in childhood B-Cell precursor acute lymphoblastic leukemia.

Authors:  Elisa Tassano; Maura Acquila; Elisa Tavella; Concetta Micalizzi; Claudio Panarello; Cristina Morerio
Journal:  Genes Chromosomes Cancer       Date:  2010-08       Impact factor: 5.006

4.  Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers.

Authors:  George Adrian Calin; Cinzia Sevignani; Calin Dan Dumitru; Terry Hyslop; Evan Noch; Sai Yendamuri; Masayoshi Shimizu; Sashi Rattan; Florencia Bullrich; Massimo Negrini; Carlo M Croce
Journal:  Proc Natl Acad Sci U S A       Date:  2004-02-18       Impact factor: 11.205

5.  RNA Sequencing Identifies Transcriptionally Viable Gene Fusions in Esophageal Adenocarcinomas.

Authors:  Andrew E Blum; Srividya Venkitachalam; Yan Guo; Ann Marie Kieber-Emmons; Lakshmeswari Ravi; Apoorva K Chandar; Prasad G Iyer; Marcia I Canto; Jean S Wang; Nicholas J Shaheen; Jill S Barnholtz-Sloan; Sanford D Markowitz; Joseph E Willis; Yu Shyr; Amitabh Chak; Vinay Varadan; Kishore Guda
Journal:  Cancer Res       Date:  2016-08-08       Impact factor: 12.701

6.  Identification of fusion genes in breast cancer by paired-end RNA-sequencing.

Authors:  Henrik Edgren; Astrid Murumagi; Sara Kangaspeska; Daniel Nicorici; Vesa Hongisto; Kristine Kleivi; Inga H Rye; Sandra Nyberg; Maija Wolf; Anne-Lise Borresen-Dale; Olli Kallioniemi
Journal:  Genome Biol       Date:  2011-01-19       Impact factor: 13.583

7.  Systems consequences of amplicon formation in human breast cancer.

Authors:  Koichiro Inaki; Francesca Menghi; Xing Yi Woo; Joel P Wagner; Pierre-Étienne Jacques; Yi Fang Lee; Phung Trang Shreckengast; Wendy WeiJia Soon; Ankit Malhotra; Audrey S M Teo; Axel M Hillmer; Alexis Jiaying Khng; Xiaoan Ruan; Swee Hoe Ong; Denis Bertrand; Niranjan Nagarajan; R Krishna Murthy Karuturi; Alfredo Hidalgo Miranda; Edison T Liu
Journal:  Genome Res       Date:  2014-09-03       Impact factor: 9.043

8.  Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types.

Authors:  Craig P Giacomini; Steven Sun; Sushama Varma; A Hunter Shain; Marilyn M Giacomini; Jay Balagtas; Robert T Sweeney; Everett Lai; Catherine A Del Vecchio; Andrew D Forster; Nicole Clarke; Kelli D Montgomery; Shirley Zhu; Albert J Wong; Matt van de Rijn; Robert B West; Jonathan R Pollack
Journal:  PLoS Genet       Date:  2013-04-25       Impact factor: 5.917

9.  Frequent miRNA-convergent fusion gene events in breast cancer.

Authors:  Helena Persson; Rolf Søkilde; Jari Häkkinen; Anna Chiara Pirona; Johan Vallon-Christersson; Anders Kvist; Fredrik Mertens; Åke Borg; Felix Mitelman; Mattias Höglund; Carlos Rovira
Journal:  Nat Commun       Date:  2017-10-05       Impact factor: 14.919
  9 in total
  1 in total

1.  Non-coding RNAs in cancers with chromosomal rearrangements: the signatures, causes, functions and implications.

Authors:  Cai Han; Lin-Yu Sun; Wen-Tao Wang; Yu-Meng Sun; Yue-Qin Chen
Journal:  J Mol Cell Biol       Date:  2019-10-25       Impact factor: 6.216
  1 in total

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