Literature DB >> 29404362

The potential detrimental effects of calcium channel blockers' overdose and current available management.

Manyoo A Agarwal1, David Flatt2, Rami N Khouzam2.   

Abstract

Calcium channel blockers (CCBs) are prescribed in a wide variety of cardiovascular conditions. Overdose of this commonly used drug can result in negative physiologic consequences including severe hypotension and even death due to metabolic and hemodynamic compromise. We report the fatal case of an amlodipine overdose, which caused intractable acidosis and cardiovascular failure in a 51-year-old male.

Entities:  

Keywords:  Calcium channel overdose; acidosis; cardiogenic shock

Year:  2018        PMID： 29404362      PMCID： PMC5787722          DOI： 10.21037/atm.2018.01.03

Source DB:  PubMed          Journal:  Ann Transl Med        ISSN： 2305-5839


  3 in total

1.  2010 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 28th Annual Report.

Authors:  Alvin C Bronstein; Daniel A Spyker; Louis R Cantilena; Jody L Green; Barry H Rumack; Richard C Dart
Journal:  Clin Toxicol (Phila)       Date:  2011-12       Impact factor: 4.467

2.  Experts Consensus Recommendations for the Management of Calcium Channel Blocker Poisoning in Adults.

Authors:  Maude St-Onge; Kurt Anseeuw; Frank Lee Cantrell; Ian C Gilchrist; Philippe Hantson; Benoit Bailey; Valéry Lavergne; Sophie Gosselin; William Kerns; Martin Laliberté; Eric J Lavonas; David N Juurlink; John Muscedere; Chen-Chang Yang; Tasnim Sinuff; Michael Rieder; Bruno Mégarbane
Journal:  Crit Care Med       Date:  2017-03       Impact factor: 7.598

3.  Calcium channel blocker overdose: experience with amlodipine.

Authors:  Supradip Ghosh; Mrinal Sircar
Journal:  Indian J Crit Care Med       Date:  2008-10
  3 in total
  1 in total

1.  Single-Pass Albumin Dialysis as Rescue Therapy for Pediatric Calcium Channel Blocker Overdose.

Authors:  Jenna Essink; Sydney Berg; Jaka Montange; Andrew Sankey; Veronica Taylor; Jeffrey Salomon
Journal:  J Investig Med High Impact Case Rep       Date:  2022 Jan-Dec
  1 in total

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