| Literature DB >> 2940429 |
A John, J P Stasch, D Neuser, C Hirth, F J Morich.
Abstract
A monoclonal antibody with specificity for atrial natriuretic peptides (ANP) was produced, that can be used for the radioimmunological determination of ANP-immunoreactivity (ANP-IR) in rat plasma. The antibody recognizes atriopeptin I, II, III, as well as alpha-hANP and alpha-hANP fragment (7-28) and does not crossreact with ANP-fragments (13-28) and (18-28). Plasma levels of ANP-IR in conscious Wistar rats were determined before and after volume-loading. Basal plasma levels of ANP-IR were 108 +/- 12 pg/ml, and after volume-loading increased to 800 +/- 59 pg/ml.Entities:
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Year: 1986 PMID： 2940429 DOI： 10.1016/0024-3205(86)90146-3
Source DB: PubMed Journal: Life Sci ISSN： 0024-3205 Impact factor: 5.037