Literature DB >> 29404166

Does the Incidence and Mortality of Pulmonary Thromboembolism Change Over the Years?

Savaş Sedat Özsu1, Zerrin Gürel Durmuş1, Mustafa Buğra Coşkuner1, Yılmaz Bülbül1, Funda Öztuna1, Tevfik Özlü1.   

Abstract

OBJECTIVES: In the last 20 years, with the use of computed tomography (CT) angiography, the number of patients diagnosed with pulmonary thromboembolism (PTE) has increased. At the same time, data show that pulmonary embolism mortality has also reduced in this duration.
MATERIAL AND METHODS: In this study, we analyzed records of patients with PTE (using ICD's) in the hospital automation system from 2001 to 2013. Data regarding age, sex, date of diagnosis, diagnosis of cancer, hemodynamic status, initial and maintenance treatment, hospital length of stay, and hospital mortality were recorded. Primary endpoints of the study were hospital length of stay and all-cause hospital mortality.
RESULTS: The total number of patients included in the study was 1185. The median age was 61 years in 2001 and 71 years in 2013. The number of patients who were diagnosed using CT increased from 10% to 92.8%. Between 2001 and 2013, the number of patients diagnosed with PTE increased, and of all patients with PTE, 13.7% was diagnosed in 2009. The hospital length of stay of 13 days declined to 9 days. The use of a vena cava filter in 2007 was 1.1% and that in 2013 was 4.6%. Mortality rate was 15%, however hospital mortality did not significantly differ over the years but varied between 9.4% and 18.8%. Increased use of thrombolytics in patients with massive PTE has been observed over the years. Massive PTE ratio in 2006 was 8.5% and thrombolytic use was 5.8%, however in 2013, these ratios were 2.6%, 6% respectively (p=0.017).
CONCLUSION: Finally, despite the increased number of patients diagnosed with PTE over the years, the mortality rate was not observed to have changed from 2001 to 2013.

Entities:  

Keywords:  Pulmonary thromboembolism; heparin; incidence; mortality; thrombolytic

Year:  2017        PMID: 29404166      PMCID: PMC5783086          DOI: 10.5152/TurkThoracJ.2017.16050

Source DB:  PubMed          Journal:  Turk Thorac J        ISSN: 2148-7197


  10 in total

1.  Combined risk stratification with computerized tomography /echocardiography and biomarkers in patients with normotensive pulmonary embolism.

Authors:  Savas Ozsu; Kayıhan Karaman; Ahmet Mentese; Asiye Ozsu; S Caner Karahan; Ismet Durmus; Funda Oztuna; Polat Kosucu; Yilmaz Bulbul; Tevfik Ozlu
Journal:  Thromb Res       Date:  2010-12       Impact factor: 3.944

2.  Analysis of National Trends in Admissions for Pulmonary Embolism.

Authors:  Sean B Smith; Jeffrey B Geske; Parul Kathuria; Michael Cuttica; Daniel R Schimmel; D Mark Courtney; Grant W Waterer; Richard G Wunderink
Journal:  Chest       Date:  2016-02-18       Impact factor: 9.410

3.  Value of Cardiac Troponin and sPESI in Treatment of Pulmonary Thromboembolism at Outpatient Setting.

Authors:  Savas Ozsu; Hayriye Bektas; Yasin Abul; Tevfik Ozlu; Asım Örem
Journal:  Lung       Date:  2015-04-04       Impact factor: 2.584

4.  Secular Trends in Incidence and Mortality of Acute Venous Thromboembolism: The AB-VTE Population-Based Study.

Authors:  Ghazi S Alotaibi; Cynthia Wu; Ambikaipakan Senthilselvan; M Sean McMurtry
Journal:  Am J Med       Date:  2016-02-27       Impact factor: 4.965

5.  Time trends and case fatality rate of in-hospital treated pulmonary embolism during 11 years of observation in Northwestern Italy.

Authors:  Francesco Dentali; Walter Ageno; Fulvio Pomero; Luigi Fenoglio; Alessandro Squizzato; Matteo Bonzini
Journal:  Thromb Haemost       Date:  2015-09-17       Impact factor: 5.249

6.  Time trends in pulmonary embolism in the United States: evidence of overdiagnosis.

Authors:  Renda Soylemez Wiener; Lisa M Schwartz; Steven Woloshin
Journal:  Arch Intern Med       Date:  2011-05-09

7.  Incidence rates, clinical profile, and outcomes of patients with venous thromboembolism. The Worcester VTE study.

Authors:  Frederick A Spencer; Cathy Emery; Samuel W Joffe; Luigi Pacifico; Darleen Lessard; George Reed; Joel M Gore; Robert J Goldberg
Journal:  J Thromb Thrombolysis       Date:  2009-11       Impact factor: 2.300

Review 8.  The Impact of Clinical Decision Rules on Computed Tomography Use and Yield for Pulmonary Embolism: A Systematic Review and Meta-analysis.

Authors:  Ralph C Wang; Stephen Bent; Ellen Weber; Jersey Neilson; Rebecca Smith-Bindman; Jahan Fahimi
Journal:  Ann Emerg Med       Date:  2015-12-31       Impact factor: 5.721

9.  Trends in the Management and Outcomes of Acute Pulmonary Embolism: Analysis From the RIETE Registry.

Authors:  David Jiménez; Javier de Miguel-Díez; Ricardo Guijarro; Javier Trujillo-Santos; Remedios Otero; Raquel Barba; Alfonso Muriel; Guy Meyer; Roger D Yusen; Manuel Monreal
Journal:  J Am Coll Cardiol       Date:  2016-01-19       Impact factor: 24.094

10.  Trends in pulmonary embolism morbidity and mortality in Australia.

Authors:  Timothy P Shiraev; Abdullah Omari; R Louise Rushworth
Journal:  Thromb Res       Date:  2013-05-29       Impact factor: 3.944

  10 in total
  2 in total

Review 1.  [Use of lung and pleural ultrasonography in emergency and intensive care medicine].

Authors:  Gebhard Mathis
Journal:  Med Klin Intensivmed Notfmed       Date:  2019-08-07       Impact factor: 0.840

2.  Diagnostic management of inpatients with a positive D-dimer test: developing a new clinical decision-making rule for pulmonary embolism.

Authors:  Min Lei; Chang Liu; Zhuang Luo; Zhibo Xu; Youfan Jiang; Jiachen Lin; Chu Wang; Depeng Jiang
Journal:  Pulm Circ       Date:  2021-01-07       Impact factor: 3.017

  2 in total

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