Literature DB >> 29403336

Experimental use of an extracellular matrix graft in pterygium surgery.

Erik W Anderson1, Suri Dwarakanathan2, Ramez Haddadin2.   

Abstract

A 40-year-old man presented with a primary pterygium of the right eye and underwent pterygium excision using mitomycin C and placement of an extracellular matrix (ECM) adjuvant. As an adjuvant in pterygium surgery, ECM serves as a scaffold while promoting the growth of normal conjunctiva. Perioperatively, the ECM graft was found to be easily manipulated on the surgical field. It attached to the scleral bed with fibrin glue without complication. Postoperatively, there was no inflammation or local tissue reaction to the porcine ECM graft. At the most recent follow-up examination, 6 months postoperatively, there were no signs of recurrence of the pterygium past the limbus. This is the first report describing the use of ECM as an adjuvant to pterygium excision.

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Mesh:

Year:  2017        PMID: 29403336      PMCID: PMC5791628          DOI: 10.5693/djo.02.2017.11.001

Source DB:  PubMed          Journal:  Digit J Ophthalmol        ISSN: 1542-8958


  6 in total

1.  [Experimental study and application of extracellular matrix of conjunctiva].

Authors:  X Meng; Q Zhang; S Tang; J Liu
Journal:  Zhonghua Yan Ke Za Zhi       Date:  2001-05

2.  Introduction to Special Issue on ocular ECM.

Authors:  Muayyad Al-Ubaidi; Matthew Petroll
Journal:  Exp Eye Res       Date:  2015-04       Impact factor: 3.467

3.  Recurrence Rate and Complications of Pterygium Extended Removal Followed by Extended Conjunctival Transplant.

Authors:  Curtis R Cornelius
Journal:  Cornea       Date:  2017-01       Impact factor: 2.651

Review 4.  Options and adjuvants in surgery for pterygium: a report by the American Academy of Ophthalmology.

Authors:  Stephen C Kaufman; Deborah S Jacobs; W Barry Lee; Sophie X Deng; Mark I Rosenblatt; Roni M Shtein
Journal:  Ophthalmology       Date:  2012-10-11       Impact factor: 12.079

5.  Galectin-3 enhances extracellular matrix associations and wound healing in monkey corneal epithelium.

Authors:  Atsuko Fujii; Thomas R Shearer; Mitsuyoshi Azuma
Journal:  Exp Eye Res       Date:  2015-06-10       Impact factor: 3.467

Review 6.  From nano to macro: studying the hierarchical structure of the corneal extracellular matrix.

Authors:  Andrew J Quantock; Moritz Winkler; Geraint J Parfitt; Robert D Young; Donald J Brown; Craig Boote; James V Jester
Journal:  Exp Eye Res       Date:  2015-04       Impact factor: 3.467

  6 in total

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