Literature DB >> 29401421

CRISPR Screens Uncover Genes that Regulate Target Cell Sensitivity to the Morphogen Sonic Hedgehog.

Ganesh V Pusapati, Jennifer H Kong, Bhaven B Patel, Arunkumar Krishnan, Andreas Sagner, Maia Kinnebrew, James Briscoe, L Aravind, Rajat Rohatgi.   

Abstract

Entities:  

Year:  2018        PMID： 29401421      PMCID： PMC5804815          DOI： 10.1016/j.devcel.2018.01.002

Source DB:  PubMed          Journal:  Dev Cell        ISSN： 1534-5807            Impact factor:   12.270


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  1 in total

1.  Centriole triplet microtubules are required for stable centriole formation and inheritance in human cells.

Authors:  Jennifer T Wang; Dong Kong; Christian R Hoerner; Jadranka Loncarek; Tim Stearns
Journal:  Elife       Date:  2017-09-14       Impact factor: 8.140
  1 in total
  12 in total

1.  Activation of G-Protein Coupled Receptor-Gαi Signaling Increases Keratinocyte Proliferation and Reduces Differentiation, Leading to Epidermal Hyperplasia.

Authors:  M Pilar Pedro; Natalia Salinas Parra; J Silvio Gutkind; Ramiro Iglesias-Bartolome
Journal:  J Invest Dermatol       Date:  2019-11-07       Impact factor: 8.551

2.  Chronic and age-dependent effects of the spongiform neurodegeneration-associated MGRN1 E3 ubiquitin ligase on mitochondrial homeostasis.

Authors:  Teresa M Gunn; Derek Silvius; Andrew Lester; Britney Gibbs
Journal:  Mamm Genome       Date:  2019-05-14       Impact factor: 2.957

Review 3.  Biochemical mechanisms of vertebrate hedgehog signaling.

Authors:  Jennifer H Kong; Christian Siebold; Rajat Rohatgi
Journal:  Development       Date:  2019-05-15       Impact factor: 6.868

4.  Rab35 controls cilium length, function and membrane composition.

Authors:  Stefanie Kuhns; Cecília Seixas; Sara Pestana; Bárbara Tavares; Renata Nogueira; Raquel Jacinto; José S Ramalho; Jeremy C Simpson; Jens S Andersen; Arnaud Echard; Susana S Lopes; Duarte C Barral; Oliver E Blacque
Journal:  EMBO Rep       Date:  2019-08-21       Impact factor: 8.807

5.  Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb and DNA methylation.

Authors:  Delphine Douillet; Christie C Sze; Caila Ryan; Andrea Piunti; Avani P Shah; Michal Ugarenko; Stacy A Marshall; Emily J Rendleman; Didi Zha; Kathryn A Helmin; Zibo Zhao; Kaixiang Cao; Marc A Morgan; Benjamin D Singer; Elizabeth T Bartom; Edwin R Smith; Ali Shilatifard
Journal:  Nat Genet       Date:  2020-05-11       Impact factor: 38.330

6.  Functional assessment of the "two-hit" model for neurodevelopmental defects in Drosophila and X. laevis.

Authors:  Lucilla Pizzo; Micaela Lasser; Tanzeen Yusuff; Matthew Jensen; Phoebe Ingraham; Emily Huber; Mayanglambam Dhruba Singh; Connor Monahan; Janani Iyer; Inshya Desai; Siddharth Karthikeyan; Dagny J Gould; Sneha Yennawar; Alexis T Weiner; Vijay Kumar Pounraja; Arjun Krishnan; Melissa M Rolls; Laura Anne Lowery; Santhosh Girirajan
Journal:  PLoS Genet       Date:  2021-04-05       Impact factor: 6.020

7.  Human pre-valvular endocardial cells derived from pluripotent stem cells recapitulate cardiac pathophysiological valvulogenesis.

Authors:  Tui Neri; Emilye Hiriart; Patrick P van Vliet; Emilie Faure; Russell A Norris; Batoul Farhat; Bernd Jagla; Julie Lefrancois; Yukiko Sugi; Thomas Moore-Morris; Stéphane Zaffran; Randolph S Faustino; Alexander C Zambon; Jean-Pierre Desvignes; David Salgado; Robert A Levine; Jose Luis de la Pompa; André Terzic; Sylvia M Evans; Roger Markwald; Michel Pucéat
Journal:  Nat Commun       Date:  2019-04-26       Impact factor: 14.919

8.  A Membrane-Tethered Ubiquitination Pathway Regulates Hedgehog Signaling and Heart Development.

Authors:  Jennifer H Kong; Cullen B Young; Ganesh V Pusapati; Chandni B Patel; Sebastian Ho; Arunkumar Krishnan; Jiuann-Huey Ivy Lin; William Devine; Anne Moreau de Bellaing; Tejas S Athni; L Aravind; Teresa M Gunn; Cecilia W Lo; Rajat Rohatgi
Journal:  Dev Cell       Date:  2020-09-22       Impact factor: 13.417

9.  Genome-wide CRISPR screen identifies ZIC2 as an essential gene that controls the cell fate of early mesodermal precursors to human heart progenitors.

Authors:  Jiejia Xu; Chikai Zhou; Kylie S Foo; Ran Yang; Yao Xiao; Kristine Bylund; Makoto Sahara; Kenneth R Chien
Journal:  Stem Cells       Date:  2020-03-10       Impact factor: 5.845

10.  Targeting of SET/I2PP2A oncoprotein inhibits Gli1 transcription revealing a new modulator of Hedgehog signaling.

Authors:  Iliana Serifi; Simoni Besta; Zoe Karetsou; Panagiota Giardoglou; Dimitris Beis; Pawel Niewiadomski; Thomais Papamarcaki
Journal:  Sci Rep       Date:  2021-07-06       Impact factor: 4.379
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