Literature DB >> 29399668

Coupling Genetic Addiction Risk Score (GARS) and Pro Dopamine Regulation (KB220) to Combat Substance Use Disorder (SUD).

Kenneth Blum1,2,3,4,5,6,7,8,9,10, Margaret A Madigan4, Lyle Fried7, Eric R Braverman6, John Giordano5, Rajendra D Badgaiyan9.   

Abstract

Entities:  

Year:  2017        PMID： 29399668      PMCID： PMC5796781          DOI： 10.19080/GJARM.2017.01.555556

Source DB:  PubMed          Journal:  Glob J Addict Rehabil Med


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  50 in total

1.  Exposure to repeated immobilization stress inhibits cocaine-induced increase in dopamine extracellular levels in the rat ventral tegmental area.

Authors:  Ramón Sotomayor-Zárate; Jorge Abarca; Katherine A Araya; Georgina M Renard; María E Andrés; Katia Gysling
Journal:  Pharmacol Res       Date:  2015-08-28       Impact factor: 7.658

Review 2.  Neurogenetics and gene therapy for reward deficiency syndrome: are we going to the Promised Land?

Authors:  Kenneth Blum; Peter K Thanos; Rajendra D Badgaiyan; Marcelo Febo; Marlene Oscar-Berman; James Fratantonio; Zsolt Demotrovics; Mark S Gold
Journal:  Expert Opin Biol Ther       Date:  2015-05-14       Impact factor: 4.388

Review 3.  The addictive brain: all roads lead to dopamine.

Authors:  Kenneth Blum; Amanda L C Chen; John Giordano; Joan Borsten; Thomas J H Chen; Mary Hauser; Thomas Simpatico; John Femino; Eric R Braverman; Debmalya Barh
Journal:  J Psychoactive Drugs       Date:  2012 Apr-Jun

4.  Parental THC exposure leads to compulsive heroin-seeking and altered striatal synaptic plasticity in the subsequent generation.

Authors:  Henrietta Szutorisz; Jennifer A DiNieri; Eric Sweet; Gabor Egervari; Michael Michaelides; Jenna M Carter; Yanhua Ren; Michael L Miller; Robert D Blitzer; Yasmin L Hurd
Journal:  Neuropsychopharmacology       Date:  2014-01-02       Impact factor: 7.853

5.  Weight gain is associated with reduced striatal response to palatable food.

Authors:  Eric Stice; Sonja Yokum; Kenneth Blum; Cara Bohon
Journal:  J Neurosci       Date:  2010-09-29       Impact factor: 6.167

6.  DNA based customized nutraceutical "gene therapy" utilizing a genoscore: a hypothesized paradigm shift of a novel approach to the diagnosis, stratification, prognosis and treatment of inflammatory processes in the human.

Authors:  Kenneth Blum; Brian Meshkin; B William Downs
Journal:  Med Hypotheses       Date:  2006-01-05       Impact factor: 1.538

Review 7.  Reward deficiency syndrome: a biogenetic model for the diagnosis and treatment of impulsive, addictive, and compulsive behaviors.

Authors:  K Blum; E R Braverman; J M Holder; J F Lubar; V J Monastra; D Miller; J O Lubar; T J Chen; D E Comings
Journal:  J Psychoactive Drugs       Date:  2000-11

Review 8.  Neurogenetics of dopaminergic receptor supersensitivity in activation of brain reward circuitry and relapse: proposing "deprivation-amplification relapse therapy" (DART).

Authors:  Kenneth Blum; Thomas J H Chen; B William Downs; Abdalla Bowirrat; Roger L Waite; Eric R Braverman; Margaret Madigan; Marlene Oscar-Berman; Nicholas DiNubile; Eric Stice; John Giordano; Siobhan Morse; Mark Gold
Journal:  Postgrad Med       Date:  2009-11       Impact factor: 3.840

9.  KB220Z™ a Pro-Dopamine Regulator Associated with the Protracted, Alleviation of Terrifying Lucid Dreams. Can We Infer Neuroplasticity-induced Changes in the Reward Circuit?

Authors:  Thomas McLaughlin; Marcelo Febo; Rajendra D Badgaiyan; Debmalya Barh; Kristina Dushaj; Eric R Braverman; Mona Li; Margaret A Madigan; Kenneth Blum
Journal:  J Reward Defic Syndr Addict Sci       Date:  2016-05-19

10.  Systematic evaluation of "compliance" to prescribed treatment medications and "abstinence" from psychoactive drug abuse in chemical dependence programs: data from the comprehensive analysis of reported drugs.

Authors:  Kenneth Blum; David Han; John Femino; David E Smith; Scott Saunders; Thomas Simpatico; Stephen J Schoenthaler; Marlene Oscar-Berman; Mark S Gold
Journal:  PLoS One       Date:  2014-09-23       Impact factor: 3.240
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  6 in total

Review 1.  Precision Behavioral Management (PBM) and Cognitive Control as a Potential Therapeutic and Prophylactic Modality for Reward Deficiency Syndrome (RDS): Is There Enough Evidence?

Authors:  Margaret A Madigan; Ashim Gupta; Abdalla Bowirrat; David Baron; Rajendra D Badgaiyan; Igor Elman; Catherine A Dennen; Eric R Braverman; Mark S Gold; Kenneth Blum
Journal:  Int J Environ Res Public Health       Date:  2022-05-24       Impact factor: 4.614

2.  Proposing a "Brain Health Checkup (BHC)" as a Global Potential "Standard of Care" to Overcome Reward Dysregulation in Primary Care Medicine: Coupling Genetic Risk Testing and Induction of "Dopamine Homeostasis".

Authors:  Eric R Braverman; Catherine A Dennen; Mark S Gold; Abdalla Bowirrat; Ashim Gupta; David Baron; A Kenison Roy; David E Smith; Jean Lud Cadet; Kenneth Blum
Journal:  Int J Environ Res Public Health       Date:  2022-04-30       Impact factor: 4.614

Review 3.  Prenatal Effects of Nicotine on Obesity Risks: A Narrative Review.

Authors:  Olivia White; Nicole Roeder; Kenneth Blum; Rina D Eiden; Panayotis K Thanos
Journal:  Int J Environ Res Public Health       Date:  2022-08-02       Impact factor: 4.614

4.  Molecular neuro-biological and systemic health benefits of achieving dopamine homeostasis in the face of a catastrophic pandemic (COVID- 19): A mechanistic exploration.

Authors:  B W Downs; K Blum; D Bagchi; S Kushner; M Bagchi; J M Galvin; McG Lewis; D Siwicki; R Brewer; B Boyett; D Baron; J Giordano; R D Badgaiyan
Journal:  J Syst Integr Neurosci       Date:  2020-04-30

5.  Would induction of dopamine homeostasis via coupling genetic addiction risk score (GARS®) and pro-dopamine regulation benefit benzodiazepine use disorder (BUD)?

Authors:  K Blum; M Gold; E J Modestino; D Baron; B Boyett; D Siwicki; L Lott; A Podesta; A K Roy; M Hauser; B W Downs; R D Badgaiyan
Journal:  J Syst Integr Neurosci       Date:  2018-05-03

Review 6.  A Review of DNA Risk Alleles to Determine Epigenetic Repair of mRNA Expression to Prove Therapeutic Effectiveness in Reward Deficiency Syndrome (RDS): Embracing "Precision Behavioral Management".

Authors:  Kenneth Blum; Bruce Steinberg; Marjorie C Gondre-Lewis; David Baron; Edward J Modestino; Rajendra D Badgaiyan; B William Downs; Debasis Bagchi; Raymond Brewer; Thomas McLaughlin; Abdalla Bowirrat; Mark Gold
Journal:  Psychol Res Behav Manag       Date:  2021-12-17
  6 in total

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