| Literature DB >> 29398799 |
Sonal Jain1, Anurag Mehta1, Gauri Kapoor2, Dinesh Bhurani3, Sandeep Jain2, Narendra Agrawal3, Rayaz Ahmed3, Dushyant Kumar1.
Abstract
Minimal residual disease is currently the most powerful prognostic indicator in Precursor B lymphoblastic leukemia. Multiparameter flow cytometry is the most commonly used modality. Seventy three B ALL cases and 15 normal marrows were evaluated for expression patterns of leukemia markers (CD38, CD58, CD73) in all 73 cases and CD66c, CD86 and CD123 in 23 cases. CD73 was aberrantly expressed in 90.41% cases and CD86 in 60.87% B ALL cases. Thus addition of these markers in MRD panels can increase the sensitivity of the assay.Entities:
Keywords: Acute leukemia; Hematology; MRD
Year: 2017 PMID: 29398799 PMCID: PMC5786637 DOI: 10.1007/s12288-017-0845-5
Source DB: PubMed Journal: Indian J Hematol Blood Transfus ISSN: 0971-4502 Impact factor: 0.900