Literature DB >> 29398624

Proceedings of the signature series event of the international society for cellular therapy: "Advancements in cellular therapies and regenerative medicine in digestive diseases," London, United Kingdom, May 3, 2017.

Rachele Ciccocioppo1, Claudia C Dos Santos2, Daniel C Baumgart3, Giuseppina C Cangemi4, Vincenzo Cardinale5, Carolina Ciacci6, Paolo De Coppi7, Debashis Haldar8, Catherine Klersy9, M Cristina Nostro10, Michael Ott11, Lorenzo Piemonti12, Alice A Tomei13, Basak Uygun14, Stefania Vetrano15, Giuseppe Orlando16.   

Abstract

A summary of the First Signature Series Event, "Advancements in Cellular Therapies and Regenerative Medicine for Digestive Diseases," held on May 3, 2017, in London, United Kingdom, is presented. Twelve speakers from three continents covered major topics in the areas of cellular therapy and regenerative medicine applied to liver and gastrointestinal medicine as well as to diabetes mellitus. Highlights from their presentations, together with an overview of the global impact of digestive diseases and a proposal for a shared online collection and data-monitoring platform tool, are included in this proceedings. Although growing evidence demonstrate the feasibility and safety of exploiting cell-based technologies for the treatment of digestive diseases, regulatory and methodological obstacles will need to be overcome before the successful implementation in the clinic of these novel attractive therapeutic strategies.
Copyright © 2017 International Society for Cellular Therapy. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  digestive diseases; immune tolerance; mesenchymal stromal cells; tissue regeneration

Mesh:

Year:  2018        PMID: 29398624      PMCID: PMC6771025          DOI: 10.1016/j.jcyt.2017.12.004

Source DB:  PubMed          Journal:  Cytotherapy        ISSN: 1465-3249            Impact factor:   5.414


  117 in total

1.  Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation.

Authors:  N D Theise; S Badve; R Saxena; O Henegariu; S Sell; J M Crawford; D S Krause
Journal:  Hepatology       Date:  2000-01       Impact factor: 17.425

2.  Purified hematopoietic stem cells can differentiate into hepatocytes in vivo.

Authors:  E Lagasse; H Connors; M Al-Dhalimy; M Reitsma; M Dohse; L Osborne; X Wang; M Finegold; I L Weissman; M Grompe
Journal:  Nat Med       Date:  2000-11       Impact factor: 53.440

3.  Bone marrow as a potential source of hepatic oval cells.

Authors:  B E Petersen; W C Bowen; K D Patrene; W M Mars; A K Sullivan; N Murase; S S Boggs; J S Greenberger; J P Goff
Journal:  Science       Date:  1999-05-14       Impact factor: 47.728

4.  The clinical course of fistulating Crohn's disease.

Authors:  S J Bell; A B Williams; P Wiesel; K Wilkinson; R C G Cohen; M A Kamm
Journal:  Aliment Pharmacol Ther       Date:  2003-05-01       Impact factor: 8.171

5.  G-CSF-primed hematopoietic stem cells or G-CSF per se accelerate recovery and improve survival after liver injury, predominantly by promoting endogenous repair programs.

Authors:  Evangelia Yannaki; Evangelia Athanasiou; Angeliki Xagorari; Varnavas Constantinou; Ioannis Batsis; Panagiotis Kaloyannidis; Evangelia Proya; Achilles Anagnostopoulos; Athanasios Fassas
Journal:  Exp Hematol       Date:  2005-01       Impact factor: 3.084

6.  The bone marrow functionally contributes to liver fibrosis.

Authors:  Francesco P Russo; Malcolm R Alison; Brian W Bigger; Eunice Amofah; Aikaterini Florou; Farhana Amin; George Bou-Gharios; Rosemary Jeffery; John P Iredale; Stuart J Forbes
Journal:  Gastroenterology       Date:  2006-05       Impact factor: 22.682

7.  Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.

Authors:  Kazutoshi Takahashi; Shinya Yamanaka
Journal:  Cell       Date:  2006-08-10       Impact factor: 41.582

8.  Transplantation of bone marrow cells reduces CCl4-induced liver fibrosis in mice.

Authors:  Isao Sakaida; Shuji Terai; Naoki Yamamoto; Koji Aoyama; Tsuyoshi Ishikawa; Hiroshi Nishina; Kiwamu Okita
Journal:  Hepatology       Date:  2004-12       Impact factor: 17.425

9.  Systemic infusion of FLK1(+) mesenchymal stem cells ameliorate carbon tetrachloride-induced liver fibrosis in mice.

Authors:  Baijun Fang; Mingxia Shi; Lianming Liao; Shaoguang Yang; Yuhao Liu; Robert Chunhua Zhao
Journal:  Transplantation       Date:  2004-07-15       Impact factor: 4.939

10.  A significant proportion of myofibroblasts are of bone marrow origin in human liver fibrosis.

Authors:  Stuart J Forbes; Francesco P Russo; Virginia Rey; Patrizia Burra; Massimo Rugge; Nicholas A Wright; Malcolm R Alison
Journal:  Gastroenterology       Date:  2004-04       Impact factor: 22.682

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  1 in total

1.  Morbidity and Mortality in Critically Ill Children. I. Pathophysiologies and Potential Therapeutic Solutions.

Authors:  Murray M Pollack; Russell Banks; Richard Holubkov; Kathleen L Meert
Journal:  Crit Care Med       Date:  2020-06       Impact factor: 7.598

  1 in total

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