Literature DB >> 29396963

Cartilage Restoration: Microfracture and Osteochondral Autograft Transplantation.

Michael L Redondo1, Adam J Beer1, Adam B Yanke1.   

Abstract

The treatment of patellofemoral cartilage defects presents several distinct challenges when compared with cartilage restoration techniques used for other compartments of the knee due to the unique anatomy and distribution of forces. The etiologies of patellofemoral articular cartilage lesions include acute traumatic instability injuries, such as dislocation and subluxation, osteochondritis dissecans, and chronic degenerative changes. Regardless of the etiology, untreated patellofemoral cartilage lesions can contribute to activity-limiting anterior knee pain. The goal of patellofemoral cartilage restoration procedures is to impart symptomatic relief and improve quality of life by repairing the articular cartilage surface and any comorbid malalignment or maltracking.Microfracture and osteochondral autograft transplantation (OAT) are two cartilage restoration procedures to consider when treating full-thickness patellofemoral chondral defects. Considered by some experts to be the gold standard therapy, microfracture is one of the most common procedures used for cartilage restoration. The technique involves the perforation of the subchondral bone plate for the release of marrow elements, filling the defect with a fibrocartilage clot repair. Though less commonly used, OAT allows defect replacement with native hyaline cartilage via autologous transplantation from a non-weight bearing area. The purpose of this article is to discuss the indication, technical considerations, and outcomes of microfracture and OAT when used for treating chondral lesions of the patellofemoral joint. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Entities:  

Mesh:

Year:  2018        PMID: 29396963     DOI: 10.1055/s-0037-1618592

Source DB:  PubMed          Journal:  J Knee Surg        ISSN: 1538-8506            Impact factor:   2.757


  18 in total

1.  Microfracture for cartilage repair in the knee: current concepts and limitations of systematic reviews.

Authors:  Sang Jun Song; Cheol Hee Park
Journal:  Ann Transl Med       Date:  2019-07

Review 2.  Progress and prospect of technical and regulatory challenges on tissue-engineered cartilage as therapeutic combination product.

Authors:  Xiaolei Guo; Yuan Ma; Yue Min; Jiayi Sun; Xinli Shi; Guobiao Gao; Lei Sun; Jiadao Wang
Journal:  Bioact Mater       Date:  2022-06-27

Review 3.  Summary Report of the Arthritis Foundation and the American Orthopaedic Foot & Ankle Society's Symposium on Targets for Osteoarthritis Research: Part 2: Treatment Options.

Authors:  Jason S Kim; Annunziato Amendola; Alexej Barg; Judith Baumhauer; James W Brodsky; Daniel M Cushman; Tyler A Gonzalez; Dennis Janisse; Michael J Jurynec; J Lawrence Marsh; Carolyn M Sofka; Thomas O Clanton; Donald D Anderson
Journal:  Foot Ankle Orthop       Date:  2022-10-14

4.  Cartilage Restoration of Patellofemoral Lesions: A Systematic Review.

Authors:  Renato Andrade; Joni Nunes; Betina B Hinckel; Jordan Gruskay; Sebastiano Vasta; Ricardo Bastos; J Miguel Oliveira; Rui L Reis; Andreas H Gomoll; João Espregueira-Mendes
Journal:  Cartilage       Date:  2019-12-17       Impact factor: 3.117

5.  Evaluation of a Cell-Free Collagen Type I-Based Scaffold for Articular Cartilage Regeneration in an Orthotopic Rat Model.

Authors:  Marta Anna Szychlinska; Giovanna Calabrese; Silvia Ravalli; Anna Dolcimascolo; Paola Castrogiovanni; Claudia Fabbi; Caterina Puglisi; Giovanni Lauretta; Michelino Di Rosa; Alessandro Castorina; Rosalba Parenti; Giuseppe Musumeci
Journal:  Materials (Basel)       Date:  2020-05-21       Impact factor: 3.623

6.  Utility of Bioabsorbable Fixation of Osteochondral Lesions in the Adolescent Knee: Outcomes Analysis With Minimum 2-Year Follow-up.

Authors:  John A Schlechter; Shawn V Nguyen; Katie L Fletcher
Journal:  Orthop J Sports Med       Date:  2019-10-28

7.  The umbilical cord mesenchymal stem cell-derived exosomal lncRNA H19 improves osteochondral activity through miR-29b-3p/FoxO3 axis.

Authors:  Litao Yan; Gejun Liu; Xing Wu
Journal:  Clin Transl Med       Date:  2021-01

Review 8.  Recent Progress in 3D Printing of Elastic and High-Strength Hydrogels for the Treatment of Osteochondral and Cartilage Diseases.

Authors:  Wenli Dai; Muyang Sun; Xi Leng; Xiaoqing Hu; Yingfang Ao
Journal:  Front Bioeng Biotechnol       Date:  2020-11-27

Review 9.  Sprifermin: Effects on Cartilage Homeostasis and Therapeutic Prospects in Cartilage-Related Diseases.

Authors:  Zongmian Song; Yusheng Li; Chunfeng Shang; Guowei Shang; Hongwei Kou; Jinfeng Li; Songfeng Chen; Hongjian Liu
Journal:  Front Cell Dev Biol       Date:  2021-12-14

10.  Hypoxic ADSCs-derived EVs promote the proliferation and chondrogenic differentiation of cartilage stem/progenitor cells.

Authors:  Ke Xue; Yongkang Jiang; Xiaodie Zhang; Jun Wu; Lin Qi; Kai Liu
Journal:  Adipocyte       Date:  2021-12       Impact factor: 4.534

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.