Literature DB >> 2939555

Local administration of various cytostatic drugs after subcutaneous immunization enhances delayed-type hypersensitivity reaction to sheep red blood cells in mice.

B T Tan, J Limpens, M Koken, H Valster, R J Scheper.   

Abstract

Delayed hypersensitivity reaction in mice was enhanced with various anti-cancer drugs administered at the site of antigenic stimulation during 4 days following sensitization. The immunopotentiating effect of the presented local chemotherapy protocol is thought to result from impairment of a regulatory circuit, with activated suppressor T cells (Ts) as target rather than Ts precursors or Ts-inducing antigen-presenting cells.

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Year:  1986        PMID: 2939555     DOI: 10.1111/j.1365-3083.1986.tb01994.x

Source DB:  PubMed          Journal:  Scand J Immunol        ISSN: 0300-9475            Impact factor:   3.487


  9 in total

1.  Enhanced antitumor effect of combination intravesical mitomycin C and bacillus Calmette-Guerin therapy in an orthotopic bladder cancer model.

Authors:  Masashi Matsushima; Minoru Horinaga; Ryuichi Fukuyama; Hitoshi Yanaihara; Eiji Kikuchi; Makoto Kawachi; Masahiro Iida; Yoko Nakahira; Mototsugu Oya; Hirotaka Asakura
Journal:  Oncol Lett       Date:  2010-11-23       Impact factor: 2.967

2.  Synergistic effects of locally administered cytostatic drugs and a surfactant on the development of delayed-type hypersensitivity to keyhole limpet haemocyanin in mice.

Authors:  J Limpens; R J Scheper
Journal:  Clin Exp Immunol       Date:  1989-11       Impact factor: 4.330

3.  Cell-mediated immunity is enhanced by cytostatic drugs continuously released at the site of antigenic stimulation.

Authors:  A M Claessen; H Valster; H Bril; S Meyer; R J Scheper
Journal:  Cancer Immunol Immunother       Date:  1989       Impact factor: 6.968

4.  Sequential intravesical mitomycin plus Bacillus Calmette-Guérin for non-muscle-invasive urothelial bladder carcinoma: translational and phase I clinical trial.

Authors:  Robert S Svatek; Xiang Ru Zhao; Edwin E Morales; Mithilesh K Jha; Timothy Y Tseng; Cory M Hugen; Vincent Hurez; Javier Hernandez; Tyler J Curiel
Journal:  Clin Cancer Res       Date:  2014-11-25       Impact factor: 12.531

5.  Effects of sequential intravesical administration of mitomycin C and bacillus Calmette-Guérin on the immune response in the guinea pig bladder.

Authors:  L T Balemans; P D Vegt; P A Steerenberg; E C De Boer; A Van Swaaij; R E De Vries; A P Van der Meijden; W Den Otter
Journal:  Urol Res       Date:  1994

6.  Alterations in dendritic cell phenotype and function associated with immunoenhancing effects of a subcutaneously administered cyclophosphamide derivative.

Authors:  J Limpens; M Van Meijer; H M Van Santen; W T Germeraad; K Hoeben-Schornagel; M Breel; R J Scheper; G Kraal
Journal:  Immunology       Date:  1991-07       Impact factor: 7.397

7.  Inhibition of T suppressor cell function by local administration of an active cyclophosphamide derivative at the sensitization site.

Authors:  J Limpens; R J Scheper
Journal:  Clin Exp Immunol       Date:  1991-06       Impact factor: 4.330

Review 8.  Systematic Review and Cumulative Analysis of the Combination of Mitomycin C plus Bacillus Calmette-Guérin (BCG) for Non-Muscle-Invasive Bladder Cancer.

Authors:  Tuo Deng; Bing Liu; Xiaolu Duan; Tao Zhang; Chao Cai; Guohua Zeng
Journal:  Sci Rep       Date:  2017-06-09       Impact factor: 4.379

9.  Advanced ovarian cancer: Vaccination site draining lymph node as target of immuno-modulative adjuvants in autologous cancer vaccine.

Authors:  Eduardo Lasalvia-Prisco; Emilio Garcia-Giralt; Silvia Cucchi; Jesús Vázquez; Leonard Robinson; John Dalton
Journal:  Biologics       Date:  2007-06
  9 in total

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