Literature DB >> 29395431

ATP Citrate Lyase: A New Player Linking Skeletal Muscle Metabolism and Epigenetics.

Haisen Li1, Vittorio Sartorelli2.   

Abstract

Intermediates generated in several metabolic processes are used to regulate transcription through covalent histone and DNA modifications. In Cell Reports, Das et al. show that acetyl-coenzyme A (acetyl-CoA) generated by ATP citrate lyase (ACL) is utilized to acetylate histone H3 at MyoD regulatory regions, resulting in increased MyoD expression and improved muscle regeneration after injury. Published by Elsevier Ltd.

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Year:  2018        PMID： 29395431      PMCID： PMC5866763          DOI： 10.1016/j.tem.2018.01.006

Source DB:  PubMed          Journal:  Trends Endocrinol Metab        ISSN： 1043-2760            Impact factor:   12.015


  12 in total

1.  ATP citrate lyase improves mitochondrial function in skeletal muscle.

Authors:  Suman Das; Frederic Morvan; Benjamin Jourde; Viktor Meier; Peter Kahle; Pascale Brebbia; Gauthier Toussaint; David J Glass; Mara Fornaro
Journal:  Cell Metab       Date:  2015-06-02       Impact factor: 27.287

Review 2.  Chromatin modifiers and the promise of epigenetic therapy in acute leukemia.

Authors:  S M Greenblatt; S D Nimer
Journal:  Leukemia       Date:  2014-03-10       Impact factor: 11.528

Review 3.  Emerging concepts of epigenetic dysregulation in hematological malignancies.

Authors:  Panagiotis Ntziachristos; Omar Abdel-Wahab; Iannis Aifantis
Journal:  Nat Immunol       Date:  2016-08-01       Impact factor: 25.606

4.  ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch.

Authors:  Steven Zhao; AnnMarie Torres; Ryan A Henry; Sophie Trefely; Martina Wallace; Joyce V Lee; Alessandro Carrer; Arjun Sengupta; Sydney L Campbell; Yin-Ming Kuo; Alexander J Frey; Noah Meurs; John M Viola; Ian A Blair; Aalim M Weljie; Christian M Metallo; Nathaniel W Snyder; Andrew J Andrews; Kathryn E Wellen
Journal:  Cell Rep       Date:  2016-10-18       Impact factor: 9.423

Review 5.  ATP-citrate lyase: genetics, molecular biology and therapeutic target for dyslipidemia.

Authors:  Amy C Burke; Murray W Huff
Journal:  Curr Opin Lipidol       Date:  2017-04       Impact factor: 4.776

6.  ATP citrate lyase inhibition can suppress tumor cell growth.

Authors:  Georgia Hatzivassiliou; Fangping Zhao; Daniel E Bauer; Charalambos Andreadis; Anthony N Shaw; Dashyant Dhanak; Sunil R Hingorani; David A Tuveson; Craig B Thompson
Journal:  Cancer Cell       Date:  2005-10       Impact factor: 31.743

Review 7.  Regulation of muscle mass by growth hormone and IGF-I.

Authors:  C P Velloso
Journal:  Br J Pharmacol       Date:  2008-06       Impact factor: 8.739

Review 8.  Metabolic Reprogramming of Stem Cell Epigenetics.

Authors:  James G Ryall; Tim Cliff; Stephen Dalton; Vittorio Sartorelli
Journal:  Cell Stem Cell       Date:  2015-12-03       Impact factor: 24.633

Review 9.  Targeting ATP-Citrate Lyase in Hyperlipidemia and Metabolic Disorders.

Authors:  Stephen L Pinkosky; Pieter H E Groot; Narendra D Lalwani; Gregory R Steinberg
Journal:  Trends Mol Med       Date:  2017-10-06       Impact factor: 11.951

Review 10.  A metabolic link to skeletal muscle wasting and regeneration.

Authors:  René Koopman; C Hai Ly; James G Ryall
Journal:  Front Physiol       Date:  2014-02-03       Impact factor: 4.566
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  2 in total

Review 1.  The vital role of ATP citrate lyase in chronic diseases.

Authors:  Amrita Devi Khwairakpam; Kishore Banik; Sosmitha Girisa; Bano Shabnam; Mehdi Shakibaei; Lu Fan; Frank Arfuso; Javadi Monisha; Hong Wang; Xinliang Mao; Gautam Sethi; Ajaikumar B Kunnumakkara
Journal:  J Mol Med (Berl)       Date:  2019-12-19       Impact factor: 4.599

2.  Biological Behavior and Lipid Metabolism of Colon Cancer Cells are Regulated by a Combination of Sterol Regulatory Element-Binding Protein 1 and ATP Citrate Lyase.

Authors:  Zhendong Qiu; Wenhong Deng; Yupu Hong; Liang Zhao; Man Li; Yongjun Guan; Yingru Su; Chen Chen; Qiao Shi; Jia Yu; Weixing Wang
Journal:  Onco Targets Ther       Date:  2021-03-01       Impact factor: 4.147
  2 in total

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