Literature DB >> 29394747

[Long-Term Survival of a Patient with Mediastinal Lymph Node Metastasis Treated with Chemo-Radiotherapy after Surgery for Cecal Cancer].

Tomohisa Nomura1, Kenji Katsumata, Tomonori Hara, Ichirou Sonoda, Kenta Kasahara, Hiroshi Kuwabara, Masatoshi Shigoka, Masanobu Enomoto, Tetsuo Ishizaki, Tetsuo Sumi, Akihiko Tsuchida.   

Abstract

In June 1997, the patient underwent an operation for cecal colon cancer pStage II .I n May 1999, a liver metastasis at S6 was detected and the patient received a partial liver resection.In April 2004, a liver metastasis in S4 was detected and another partial liver resection was performed.In November 2008, he complained of hemoptysis and cough.The chest CT examination showed lymph node metastases in the mediastinum that invaded the left main bronchus.We performed chemo-radiotherapy for local control from January 2009. Because the lymph nodes were reduced remarkably and clinical complaints disappeared, we administrated a mFOLFOX6 regimen from June.We recognized the effect of treatment to be a complete response.In February 2014, we detected a lymph nodes recurrence around a right pulmonary artery.We performed chemo-radiotherapy again because the patient declined surgery.However, lymph node metastases did not completely respond.We then performed chemotherapy 30 times using a FOLFIRI plus panitumumab regimen.On PET-CT, the recurrent lesion did not show a hot spot.We experienced a case that responded to chemo-radiotherapy for long-term control of lymph node recurrence.

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Year:  2017        PMID: 29394747

Source DB:  PubMed          Journal:  Gan To Kagaku Ryoho        ISSN: 0385-0684


  1 in total

1.  Solitary anterior mediastinal lymph node metastasis with pericardial invasion from colon cancer: A case report.

Authors:  Yoshifumi Watanabe; Rei Suzuki; Mitsuru Kinoshita; Masashi Hirota
Journal:  Mol Clin Oncol       Date:  2022-06-20
  1 in total

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