| Literature DB >> 29393938 |
Adam M Wawro1, Yusuke Aoki, Takahiro Muraoka, Kouhei Tsumoto, Kazushi Kinbara.
Abstract
Here we report an example of a protein-PEG conjugate with a biotin tag cleavable by lipase-catalyzed hydrolysis. Very mild cleavage conditions, heterogeneous, easily separable catalysts, and traceless design make this method attractive for the preparation and purification of PEGylated proteins.Entities:
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Year: 2018 PMID： 29393938 DOI： 10.1039/c7cc05814d
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222