Literature DB >> 29392151

Pearl-White Gallstones Causing Choledocholithiasis.

Patrick Stoner1, Alexander Schlachterman2, Eric Hilgenfeldt1, Peter Draganov2.   

Abstract

Entities:  

Year:  2018        PMID: 29392151      PMCID: PMC5772062          DOI: 10.14309/crj.2018.4

Source DB:  PubMed          Journal:  ACG Case Rep J        ISSN: 2326-3253


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Case Report

A 71-year-old woman who had previously undergone cholecystectomy several years prior presented with nausea, vomiting, and right upper quadrant abdominal pain. Computed tomography of her abdomen revealed a dilated common bile duct measuring 11 mm in diameter. She underwent endoscopic retrograde cholangiopancreatography (ERCP) for evaluation. A sphincterotomy with balloon extraction revealed several white stones as the cause of her choledocholithiasis (Figure 1). Her symptoms resolved, and she fully recovered to her previous state of health.
Figure 1

(A) A large stone adjacent to the ampulla after balloon extraction at ERCP. (B) Three pearl-white stones in the duodenum. (C) Triangular pearl-white stone on gauze after ERCP.

(A) A large stone adjacent to the ampulla after balloon extraction at ERCP. (B) Three pearl-white stones in the duodenum. (C) Triangular pearl-white stone on gauze after ERCP. Gallstones have traditionally been divided into 3 main categories based on cholesterol content: cholesterol stones (cholesterol content >70%), mixed stones (cholesterol content 30–70%), and pigment stones (i.e., black or brown stones, cholesterol content <30%).1-3 Cholesterol stones consist of cholesterol monohydrate and can also include a mixture of calcium salts, bile acids, pigments, and glycoprotein (with the major components being cholesterol and protein constituents).2,4 Mixed stones are composed of varying amounts of cholesterol and the above components. Cholesterol stones usually range in color from pale yellow to yellow-green or brownish yellow, and they are round or oval with smooth surfaces.2 The stones in our case were presumed to be cholesterol stones given their light color and characteristic shape and appearance; however, their composition was never analyzed in the laboratory. Our literature review of studied gallstones did not reveal any combination of chemical components known to cause a pearl-white color as seen in our case. Thus, we report this case as a rare finding on ERCP.

Disclosures

Author contributions: P. Stoner performed the literature review and wrote the manuscript. A. Schlachterman provided the images, performed the literature review, and edited the manuscript. E. Hilgenfeldt edited the manuscript. P. Draganov edited the manuscript and is the article guarantor. Financial disclosure: None to report Informed consent was obtained for this case report. This publication is the only valid version of this article.
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1.  Concept of the pathogenesis and treatment of cholelithiasis.

Authors:  Vasiliy Ivanovich Reshetnyak
Journal:  World J Hepatol       Date:  2012-02-27

2.  Like a pearl: a rare, white, common bile duct stone in an elderly adult.

Authors:  Mevlut Hamamci; Fatih Karaahmet; Fuat Ekiz; Osman Yuksel; Omer Başar; Sahin Coban
Journal:  J Am Geriatr Soc       Date:  2014-09       Impact factor: 5.562

3.  The systematic classification of gallbladder stones.

Authors:  Tie Qiao; Rui-hong Ma; Xiao-bing Luo; Liu-qing Yang; Zhen-liang Luo; Pei-ming Zheng
Journal:  PLoS One       Date:  2013-10-04       Impact factor: 3.240

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1.  Multiple gallstones causing ileus twenty years after cholecystectomy.

Authors:  Peter Petrillo; Donald Green; Susan Haag; John Kepros
Journal:  J Surg Case Rep       Date:  2022-09-28
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