Erkan Eşki1, Belgin Emine Usta2, Suna Asilsoy2, İsmail Yılmaz3. 1. Department of Otorhinolaryngology, Başkent University İzmir Hospital, İzmir, Turkey. 2. Department of Pediatrics, Başkent University Adana Hospital, Adana, Turkey. 3. Department of Otorhinolaryngology, Başkent University Adana Hospital, Adana, Turkey.
Abstract
OBJECTIVE: To assess hearing functions in pediatric patients with selective immunoglobulin A (IgA) deficiency (SIGAD). METHODS: Pure-tone audiometry, acoustic impedance, otoacoustic emission, and brainstem audiometric measurements were taken during a non-infectious period in 28 patients with SIGAD and 28 healthy children with normal otoscopic examination. The results of the hearing tests were compared between the two groups. RESULTS: Two male patients and one female patient in the SIGAD group were found to have sensorineural hearing loss (SNHL). However, a comparison of the average pure tone cut-off values at 0.5, 1, 2, and 4 kHz did not reveal any statistically significant difference between the groups (p>0.05). CONCLUSION: Pediatric patients with SIGAD may exhibit SNHL at certain frequencies and require follow-up for the potential development of hearing loss.
OBJECTIVE: To assess hearing functions in pediatric patients with selective immunoglobulin A (IgA) deficiency (SIGAD). METHODS: Pure-tone audiometry, acoustic impedance, otoacoustic emission, and brainstem audiometric measurements were taken during a non-infectious period in 28 patients with SIGAD and 28 healthy children with normal otoscopic examination. The results of the hearing tests were compared between the two groups. RESULTS: Two male patients and one female patient in the SIGAD group were found to have sensorineural hearing loss (SNHL). However, a comparison of the average pure tone cut-off values at 0.5, 1, 2, and 4 kHz did not reveal any statistically significant difference between the groups (p>0.05). CONCLUSION: Pediatric patients with SIGAD may exhibit SNHL at certain frequencies and require follow-up for the potential development of hearing loss.
Entities:
Keywords:
Sensorineural hearing loss; pediatric; primary immunodeficiency; selective IgA deficiency
Authors: Moo-Jin Baek; Hyun-Min Park; Justin M Johnson; Cengiz Z Altuntas; Daniel Jane-Wit; Ritika Jaini; C Arturo Solares; Dawn M Thomas; Edward J Ball; Nahid G Robertson; Cynthia C Morton; Gordon B Hughes; Vincent K Tuohy Journal: J Immunol Date: 2006-09-15 Impact factor: 5.422