Literature DB >> 29391993

Tumor Microenvironment in Head and Neck Squamous Cell Carcinomas.

Görkem Eskiizmir1.   

Abstract

Recent studies about solid tumors demonstrated that tumor microenvironment has an important role in tumor progression, aggressivity, and metastasis process, in addition to genetic aberrations and molecular alterations of cancer cells. Therefore, the crosstalks between cancerous and noncancerous cells and metabolic changes in tumor microenvironment cause significant detrimental effects. The purpose of this review is to present the role and effect of noncancerous cells and their crosstalks with cancer cells, metabolic changes in tumor microenvironment, and to discuss the clinical significance of all these factors with respect to the current literature.

Entities:  

Keywords:  Carcinoma; head and neck neoplasms; squamous cell of head and neck; tumor microenvironment

Year:  2015        PMID： 29391993      PMCID： PMC5782915          DOI： 10.5152/tao.2015.1065

Source DB:  PubMed          Journal:  Turk Arch Otorhinolaryngol        ISSN： 2667-7466


  55 in total

1.  The tumor microenvironment at a glance.

Authors:  Frances R Balkwill; Melania Capasso; Thorsten Hagemann
Journal:  J Cell Sci       Date:  2012-12-01       Impact factor: 5.285

2.  Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck.

Authors:  M Nordsmark; M Overgaard; J Overgaard
Journal:  Radiother Oncol       Date:  1996-10       Impact factor: 6.280

Review 3.  Hypoxia and aggressive tumor phenotype: implications for therapy and prognosis.

Authors:  Peter Vaupel
Journal:  Oncologist       Date:  2008

Review 4.  Tumor microenvironmental physiology and its implications for radiation oncology.

Authors:  Peter Vaupel
Journal:  Semin Radiat Oncol       Date:  2004-07       Impact factor: 5.934

Review 5.  Clinical relevance of immune parameters in the tumor microenvironment of head and neck cancers.

Authors:  Sebastian P Wallis; Nicholas D Stafford; John Greenman
Journal:  Head Neck       Date:  2014-07-10       Impact factor: 3.147

6.  Prognostic significance of tumor-associated macrophages in solid tumor: a meta-analysis of the literature.

Authors:  Qiong-wen Zhang; Lei Liu; Chang-yang Gong; Hua-shan Shi; Yun-hui Zeng; Xiao-ze Wang; Yu-wei Zhao; Yu-quan Wei
Journal:  PLoS One       Date:  2012-12-28       Impact factor: 3.240

Review 7.  Chronic inflammation and cytokines in the tumor microenvironment.

Authors:  Glauben Landskron; Marjorie De la Fuente; Peti Thuwajit; Chanitra Thuwajit; Marcela A Hermoso
Journal:  J Immunol Res       Date:  2014-05-13       Impact factor: 4.818

Review 8.  Imaging hypoxia in tumours with advanced MRI.

Authors:  J M Price; S P Robinson; D M Koh
Journal:  Q J Nucl Med Mol Imaging       Date:  2013-09       Impact factor: 2.346

9.  Trial watch: Prognostic and predictive value of the immune infiltrate in cancer.

Authors:  Laura Senovilla; Erika Vacchelli; Jerome Galon; Sandy Adjemian; Alexander Eggermont; Wolf Hervé Fridman; Catherine Sautès-Fridman; Yuting Ma; Eric Tartour; Laurence Zitvogel; Guido Kroemer; Lorenzo Galluzzi
Journal:  Oncoimmunology       Date:  2012-11-01       Impact factor: 8.110

Review 10.  Hypoxia in head and neck cancer in theory and practice: a PET-based imaging approach.

Authors:  Loredana G Marcu; Wendy M Harriss-Phillips; Sanda M Filip
Journal:  Comput Math Methods Med       Date:  2014-08-21       Impact factor: 2.238
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  2 in total

1.  Prognostic and clinicopathological significance of tumor-stroma ratio in head and neck squamous cell carcinoma: A systematic review.

Authors:  E-F Morais; H-G Morais; H-D Martins; L-M Carlan; A-D Costa; R-D Freitas
Journal:  Med Oral Patol Oral Cir Bucal       Date:  2022-07-01

2.  Correlation Between the Expression of Matrix Metalloproteinase-9, Matrix Metalloproteinase-13, Tissue Inhibitor of Metalloproteinases-1, p16 and Differentiation of Head and Neck Squamous Cell Carcinoma: A Prospective Observational Study.

Authors:  Kapil Soni; Poonam Elhence; Darwin Kaushal; Nikhil Rajan; Amit Goyal; Bikram Choudhury; Vidhu Sharma
Journal:  Ann Maxillofac Surg       Date:  2021-07-24
  2 in total

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