Literature DB >> 29388638

Developing ciprofloxacin analogues against plant DNA gyrase: a novel herbicide mode of action.

Michael D Wallace1, Nidda F Waraich, Aleksandra W Debowski, Maxime G Corral, Anthony Maxwell, Joshua S Mylne, Keith A Stubbs.   

Abstract

Ciprofloxacin has been shown to exhibit potent herbicidal activity through action against plant DNA gyrase, presenting a novel mode of action. Analogues of ciprofloxacin have been prepared with increased herbicidal activity and diminished antibacterial activity, compared to ciprofloxacin, as demonstrated using model systems.

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Year:  2018        PMID: 29388638     DOI: 10.1039/c7cc09518j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  2 in total

Review 1.  Current Status and Future Prospects in Herbicide Discovery.

Authors:  Franck E Dayan
Journal:  Plants (Basel)       Date:  2019-09-11

2.  Inhibition of chloroplast translation as a new target for herbicides.

Authors:  Kirill V Sukhoverkov; Karen J Breese; Aleksandra W Debowski; Monika W Murcha; Keith A Stubbs; Joshua S Mylne
Journal:  RSC Chem Biol       Date:  2021-11-10
  2 in total

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