| Literature DB >> 29388304 |
Hulya Nalcacioglu1, Y Kamil Yakupoglu2, Gurkan Genc1, Nursen Belet3, Sema Gulnar Sensoy3, Asuman Birinci4, Ozan Ozkaya5.
Abstract
Renal transplant recipients are on long-term potent immunosuppressive therapy, which makes them highly vulnerable to opportunistic fungal infections. Dematiaceous, or dark-pigmented saprophytic fungi, are being increasingly seen as opportunistic pathogens of mycoses in immunosuppressed patients. One of these is Aureobasidium pullulans, which is a black yeast-like dematiaceous fungus found ubiquitously in the environment that can cause various opportunistic human infections. Most infections occur by traumatic inoculation, such as keratitis and cutaneous lesions; disseminated mycoses are very rare and occur only in severely immunocompromised patients. We report a case of disseminated fungal infection due to A. pullulans in a pediatric patient who underwent renal transplant. The use of voriconazole and vacuum-assisted closure along with surgical drainage most likely contributed to the patient's positive outcome.Entities:
Keywords: zzm321990Aureobasidium pullulanszzm321990; fungal infection; pediatrics; renal transplant; vacuum-assisted closure therapy
Mesh:
Year: 2018 PMID: 29388304 DOI: 10.1111/petr.13152
Source DB: PubMed Journal: Pediatr Transplant ISSN: 1397-3142