| Literature DB >> 29387466 |
Martin R Cowie1, Michel Komajda1.
Abstract
QUALIFY (QUality of Adherence to guideline recommendations for LIFe-saving treatment in heart failure surveY) showed that good physician adherence to guideline recommendations for angiotensin converting enzyme inhibitors/angiotensin receptor blockers, beta blockers, mineralocorticoid receptor antagonists and ivabradine, with prescription of at least 50 % of recommended dosages, was associated with better 6-month outcomes than moderate or poor adherence. Poor adherence was associated with higher all-cause mortality (hazard ratio 2.21; 95 % CI [1.42-3.44]; p=0.001) and combined heart failure hospitalisation or death (hazard ratio 1.26; 95 % CI [1.08-1.71]; p=0.024) compared with good adherence. Heart failure hospitalisation is a good opportunity to review a patient's medication and to optimise guideline adherence.Entities:
Keywords: Heart failure; adherence; dosage; guidelines; hospitalisation; medication; mortality
Year: 2017 PMID: 29387466 PMCID: PMC5739897 DOI: 10.15420/cfr.2017:13:1
Source DB: PubMed Journal: Card Fail Rev ISSN: 2057-7540