Literature DB >> 29386977

Sample Size Calculation in Animal Studies Using Resource Equation Approach.

Wan Nor Arifin1, Wan Mohd Zahiruddin2.   

Abstract

Animal research plays an important role in the pre-clinical phase of clinical trials. In animal studies, the power analysis approach to sample size calculation is recommended. Whenever it is not possible to assume the standard deviation and the effect size, an alternative to the power analysis approach is the 'resource equation' approach, which sets the acceptable range of the error degrees of freedom (DF) in an analysis of variance (ANOVA). The aim of this article is to guide researchers in calculating the minimum and maximum numbers of animals required in animal research by reformulating the error DF formulas.

Keywords:  animal research; research design; sample size

Year:  2017        PMID： 29386977      PMCID： PMC5772820          DOI： 10.21315/mjms2017.24.5.11

Source DB:  PubMed          Journal:  Malays J Med Sci        ISSN： 1394-195X


  6 in total

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