Literature DB >> 29384431

Epigenetic mechanisms in health and disease: BCEC 2017.

Albert Carbonell1,2, Raquel Fueyo1, Andrea Izquierdo-Bouldstridge1, Cristina Moreta3, Albert Jordan1.   

Abstract

The Barcelona Conference on Epigenetics and Cancer (BCEC) entitled "Epigenetic Mechanisms in Health and Disease" was held in Barcelona, October 26-26, 2017. The 2017 BCEC was the fifth and last edition of a series of annual conferences organized as a joint effort of five leading Barcelona research institutes together with B-Debate. This edition was organized by Albert Jordan from the Molecular Biology Institute of Barcelona (IBMB-CSIC) and Marcus Bushbeck from the Josep Carreras Leukaemia Research Institute (IJC). Jordi Bernués, Marian Martínez-Balbás, and Ferran Azorín were also part of the scientific committee. In 22 talks and 51 posters, researchers presented their latest results in the fields of histone variants, epigenetic regulation, and chromatin 3D organization to an audience of around 250 participants from 16 countries. This year, a broad number of talks focused on the epigenetic causes and possible related treatments of complex diseases such as cancer. Participants at the 2017 BCEC elegantly closed the series, discussing progress made in the field of epigenetics and highlighting its role in human health and disease.

Entities:  

Keywords:  Epigenetics; cancer; chromatin; histones; nuclear organization; stem cells

Mesh:

Substances:

Year:  2018        PMID: 29384431      PMCID: PMC5997171          DOI: 10.1080/15592294.2018.1434391

Source DB:  PubMed          Journal:  Epigenetics        ISSN: 1559-2294            Impact factor:   4.528


  81 in total

Review 1.  Histone variants in pluripotency and disease.

Authors:  Peter J Skene; Steven Henikoff
Journal:  Development       Date:  2013-06       Impact factor: 6.868

Review 2.  Transcriptional regulation by Polycomb group proteins.

Authors:  Luciano Di Croce; Kristian Helin
Journal:  Nat Struct Mol Biol       Date:  2013-10       Impact factor: 15.369

Review 3.  The interplay of epigenetic marks during stem cell differentiation and development.

Authors:  Yaser Atlasi; Hendrik G Stunnenberg
Journal:  Nat Rev Genet       Date:  2017-08-14       Impact factor: 53.242

4.  A locus control region at -12 kb of the tyrosinase gene.

Authors:  L Montoliu; T Umland; G Schütz
Journal:  EMBO J       Date:  1996-11-15       Impact factor: 11.598

Review 5.  Artificial chromosome transgenesis in pigmentary research.

Authors:  Patricia Giraldo; Lluís Montoliu
Journal:  Pigment Cell Res       Date:  2002-08

6.  EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation.

Authors:  Wendy Béguelin; Relja Popovic; Matt Teater; Yanwen Jiang; Karen L Bunting; Monica Rosen; Hao Shen; Shao Ning Yang; Ling Wang; Teresa Ezponda; Eva Martinez-Garcia; Haikuo Zhang; Yupeng Zheng; Sharad K Verma; Michael T McCabe; Heidi M Ott; Glenn S Van Aller; Ryan G Kruger; Yan Liu; Charles F McHugh; David W Scott; Young Rock Chung; Neil Kelleher; Rita Shaknovich; Caretha L Creasy; Randy D Gascoyne; Kwok-Kin Wong; Leandro Cerchietti; Ross L Levine; Omar Abdel-Wahab; Jonathan D Licht; Olivier Elemento; Ari M Melnick
Journal:  Cancer Cell       Date:  2013-05-13       Impact factor: 31.743

7.  Nucleosome-free region dominates histone acetylation in targeting SWR1 to promoters for H2A.Z replacement.

Authors:  Anand Ranjan; Gaku Mizuguchi; Peter C FitzGerald; Debbie Wei; Feng Wang; Yingzi Huang; Ed Luk; Christopher L Woodcock; Carl Wu
Journal:  Cell       Date:  2013-09-12       Impact factor: 41.582

8.  Histone demethylase KDM5A regulates the ZMYND8-NuRD chromatin remodeler to promote DNA repair.

Authors:  Fade Gong; Thomas Clouaire; Marion Aguirrebengoa; Gaëlle Legube; Kyle M Miller
Journal:  J Cell Biol       Date:  2017-06-01       Impact factor: 10.539

9.  EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop.

Authors:  Wendy Béguelin; Martín A Rivas; María T Calvo Fernández; Matt Teater; Alberto Purwada; David Redmond; Hao Shen; Matt F Challman; Olivier Elemento; Ankur Singh; Ari M Melnick
Journal:  Nat Commun       Date:  2017-10-12       Impact factor: 14.919

10.  Bromodomain inhibition shows antitumoral activity in mice and human luminal breast cancer.

Authors:  Montserrat Pérez-Salvia; Laia Simó-Riudalbas; Pere Llinàs-Arias; Laura Roa; Fernando Setien; Marta Soler; Manuel Castro de Moura; James E Bradner; Eva Gonzalez-Suarez; Catia Moutinho; Manel Esteller
Journal:  Oncotarget       Date:  2017-05-29
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