Literature DB >> 29384404

A novel fusion of PDGFRB to TSC1, an intrinsic suppressor of mTOR-signaling pathway, in a chronic eosinophilic leukemia patient with t(5;9)(q32;q34).

Yue Zhang1,2, Shiqiang Qu1, Qianfei Wang3, Jianyong Li4, Zefeng Xu1, Tiejun Qin1, Gang Huang5, Zhijian Xiao1,2.   

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Year:  2018        PMID： 29384404      PMCID： PMC9204506          DOI： 10.1080/10428194.2018.1427855

Source DB:  PubMed          Journal:  Leuk Lymphoma        ISSN： 1026-8022


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  11 in total

1.  Fusion of PDGFRB to MPRIP, CPSF6, and GOLGB1 in three patients with eosinophilia-associated myeloproliferative neoplasms.

Authors:  Nicole Naumann; Juliana Schwaab; Georgia Metzgeroth; Mohamad Jawhar; Claudia Haferlach; Gudrun Göhring; Brigitte Schlegelberger; Christian T Dietz; Susanne Schnittger; Sina Lotfi; Michael Gärtner; Tu-Anh Dang; Wolf-Karsten Hofmann; Nicholas C P Cross; Andreas Reiter; Alice Fabarius
Journal:  Genes Chromosomes Cancer       Date:  2015-09-10       Impact factor: 5.006

Review 2.  m-TOR inhibitors and their potential role in haematological malignancies.

Authors:  Teresa Calimeri; Andrés J M Ferreri
Journal:  Br J Haematol       Date:  2017-02-01       Impact factor: 6.998

3.  Interaction between hamartin and tuberin, the TSC1 and TSC2 gene products.

Authors:  M van Slegtenhorst; M Nellist; B Nagelkerken; J Cheadle; R Snell; A van den Ouweland; A Reuser; J Sampson; D Halley; P van der Sluijs
Journal:  Hum Mol Genet       Date:  1998-06       Impact factor: 6.150

4.  Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34.

Authors:  M van Slegtenhorst; R de Hoogt; C Hermans; M Nellist; B Janssen; S Verhoef; D Lindhout; A van den Ouweland; D Halley; J Young; M Burley; S Jeremiah; K Woodward; J Nahmias; M Fox; R Ekong; J Osborne; J Wolfe; S Povey; R G Snell; J P Cheadle; A C Jones; M Tachataki; D Ravine; J R Sampson; M P Reeve; P Richardson; F Wilmer; C Munro; T L Hawkins; T Sepp; J B Ali; S Ward; A J Green; J R Yates; J Kwiatkowska; E P Henske; M P Short; J H Haines; S Jozwiak; D J Kwiatkowski
Journal:  Science       Date:  1997-08-08       Impact factor: 47.728

5.  Rapamycin induces feedback activation of Akt signaling through an IGF-1R-dependent mechanism.

Authors:  X Wan; B Harkavy; N Shen; P Grohar; L J Helman
Journal:  Oncogene       Date:  2006-09-25       Impact factor: 9.867

6.  Imatinib in myeloid/lymphoid neoplasms with eosinophilia and rearrangement of PDGFRB in chronic or blast phase.

Authors:  Mohamad Jawhar; Nicole Naumann; Juliana Schwaab; Herrad Baurmann; Jochen Casper; Tu-Anh Dang; Lutz Dietze; Konstanze Döhner; Annette Hänel; Bernd Lathan; Hartmut Link; Sina Lotfi; Ole Maywald; Stephan Mielke; Lothar Müller; Uwe Platzbecker; Otto Prümmer; Henrike Thomssen; Karin Töpelt; Jens Panse; Tom Vieler; Wolf-Karsten Hofmann; Torsten Haferlach; Claudia Haferlach; Alice Fabarius; Andreas Hochhaus; Nicholas C P Cross; Andreas Reiter; Georgia Metzgeroth
Journal:  Ann Hematol       Date:  2017-07-19       Impact factor: 3.673

Review 7.  The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia.

Authors:  Daniel A Arber; Attilio Orazi; Robert Hasserjian; Jürgen Thiele; Michael J Borowitz; Michelle M Le Beau; Clara D Bloomfield; Mario Cazzola; James W Vardiman
Journal:  Blood       Date:  2016-04-11       Impact factor: 22.113

Review 8.  The TSC1-TSC2 complex: a molecular switchboard controlling cell growth.

Authors:  Jingxiang Huang; Brendan D Manning
Journal:  Biochem J       Date:  2008-06-01       Impact factor: 3.857

9.  Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2.

Authors:  Morris E Feldman; Beth Apsel; Aino Uotila; Robbie Loewith; Zachary A Knight; Davide Ruggero; Kevan M Shokat
Journal:  PLoS Biol       Date:  2009-02-10       Impact factor: 8.029

10.  Rapamycin-resistant and torin-sensitive mTOR signaling promotes the survival and proliferation of leukemic cells.

Authors:  Seohyun Park; Hyunsub Sim; Keunwook Lee
Journal:  BMB Rep       Date:  2016-01       Impact factor: 4.778
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  2 in total

1.  A novel fusion gene involving PDGFRB and GCC2 in a chronic eosinophilic leukemia patient harboring t(2;5)(q37;q31).

Authors:  Noriyoshi Iriyama; Hiromichi Takahashi; Hiromu Naruse; Katsuhiro Miura; Yoshihito Uchino; Masaru Nakagawa; Kazuhide Iizuka; Takashi Hamada; Yoshihiro Hatta; Tomohiro Nakayama; Masami Takei
Journal:  Mol Genet Genomic Med       Date:  2019-01-29       Impact factor: 2.183

2.  Comprehensive Investigation of miRNome Identifies Novel Candidate miRNA-mRNA Interactions Implicated in T-Cell Acute Lymphoblastic Leukemia.

Authors:  Małgorzata Dawidowska; Roman Jaksik; Monika Drobna; Bronisława Szarzyńska-Zawadzka; Maria Kosmalska; Łukasz Sędek; Ludomiła Machowska; Anna Lalik; Monika Lejman; Marek Ussowicz; Krzysztof Kałwak; Jerzy R Kowalczyk; Tomasz Szczepański; Michał Witt
Journal:  Neoplasia       Date:  2019-02-11       Impact factor: 5.715
  2 in total

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